Gene: ZDHHC6
Official Full Name: zDHHC palmitoyltransferase 6provided by HGNC
Gene Summary: Enables palmitoyltransferase activity and protein-cysteine S-stearoyltransferase activity. Involved in positive regulation of mitochondrial fusion; protein palmitoylation; and protein stearoylation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12432 | ZDHHC6 Knockout cell line (HeLa) | Human | ZDHHC6 | 1:3~1:6 | Negative | Online Inquiry |
KO12433 | ZDHHC6 Knockout cell line (HCT 116) | Human | ZDHHC6 | 1:2~1:4 | Negative | Online Inquiry |
KO12434 | ZDHHC6 Knockout cell line (HEK293) | Human | ZDHHC6 | 1:3~1:6 | Negative | Online Inquiry |
KO12435 | ZDHHC6 Knockout cell line (A549) | Human | ZDHHC6 | 1:3~1:4 | Negative | Online Inquiry |
ZDHHC6 Gene Knockout Cell Lines are genetically engineered cell lines where the ZDHHC6 gene, a crucial component implicated in various cellular processes, has been inactivated through targeted gene editing techniques. These knockout cell lines serve as essential tools for investigating the biological functions of ZDHHC6, which is known to play a significant role in palmitoylation—a post-translational modification that affects protein localization, stability, and interaction. By eliminating ZDHHC6 expression, researchers can explore the gene’s involvement in signaling pathways and disease mechanisms, including cancer progression and neurodegenerative disorders.
The primary function of ZDHHC6 Gene Knockout Cell Lines is to provide a controlled environment for studying the absence of ZDHHC6 and its effects on cellular behavior. Researchers can utilize these cell lines to dissect the downstream impacts on palmitoylation and its consequences on cellular dynamics, thereby enabling the identification of potential therapeutic targets. In clinical applications, these cell lines may also facilitate drug screening processes and offer insights into patient-specific responses to treatments.
Compared to traditional cell lines, ZDHHC6 Gene Knockout Cell Lines present distinct advantages such as high specificity and reliability in studying gene function. While alternative methods like RNA interference can transiently reduce gene expression, knockout models provide a permanent solution, leading to more consistent and reproducible experimental conditions. The reliability of knockout models enhances the depth of analysis possible in experimental research, allowing for greater insights into gene function.
The value of ZDHHC6 Gene Knockout Cell Lines to researchers and clinicians cannot be overstated—they empower the scientific community to unravel the complexities of protein modifications and their roles in health and disease, thus potentially paving the way for novel therapeutic strategies. With our extensive experience in genetic engineering and cell line development, our company is dedicated to providing high-quality biological products that advance the frontiers of biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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