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ZDHHC3 Knockout Cell Lines

Gene: ZDHHC3

Official Full Name: zDHHC palmitoyltransferase 3provided by HGNC

Gene Summary: Enables palmitoyltransferase activity. Involved in several processes, including protein localization to membrane; protein localization to photoreceptor outer segment; and regulation of signal transduction. Located in membrane. Is active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22704 ZDHHC3 Knockout cell line (HeLa) Human ZDHHC3 1:3~1:6 Negative Online Inquiry
KO22705 ZDHHC3 Knockout cell line (HCT 116) Human ZDHHC3 1:2~1:4 Negative Online Inquiry
KO22706 ZDHHC3 Knockout cell line (HEK293) Human ZDHHC3 1:3~1:6 Negative Online Inquiry
KO22707 ZDHHC3 Knockout cell line (A549) Human ZDHHC3 1:3~1:4 Negative Online Inquiry

Background

ZDHHC3 Gene Knockout Cell Lines are genetically engineered cell lines that have had the ZDHHC3 gene inactivated, allowing researchers to investigate the functional roles of this gene in cellular processes. ZDHHC3 encodes for a palmitoyl transferase involved in the regulation of various signaling pathways, notably those related to cellular growth, differentiation, and survival. The key functionality of these knockout cell lines lies in their ability to provide insights into the mechanistic underpinnings of protein palmitoylation and its influence on cellular behavior, particularly in the context of cancer biology and neurodevelopment.

The significance of ZDHHC3 Gene Knockout Cell Lines extends into both basic research and clinical applications. In research settings, these cell lines serve as vital tools in elucidating the contributions of ZDHHC3 to disease mechanisms, making them invaluable for identifying potential therapeutic targets. Clinically, they support the development of treatments that could modulate the activity of palmitoyl transferases, subsequently affecting pathways involved in tumorigenesis and other pathologies.

One of the unique selling points of ZDHHC3 Gene Knockout Cell Lines is their precision; researchers can rely on the reproducibility of knockout models to obtain consistent and reliable data. Additionally, these cell lines provide a straightforward approach to investigate compensation by other ZDHHC family members, an essential consideration often overlooked in studies involving genetic mutations. Compared to alternative models, such as transient knockdowns which often lead to variable results, our knockout lines offer stable expression profiles, permitting long-term studies on cellular dynamics.

These cell lines hold substantial value for researchers and clinicians aiming to deepen their understanding of gene function and its implications in disease. Our company boasts a strong track record in developing high-quality, validated biological products, ensuring that scientists have access to reliable and relevant tools essential for advancing their research projects. By selecting ZDHHC3 Gene Knockout Cell Lines, users are investing in a resource that combines precision with essential biological insight, fostering advancements in both scientific discovery and clinical therapeutics.

Please note that all services are for research use only. Not intended for any clinical use.

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