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ZDHHC24 Knockout Cell Lines

Gene: ZDHHC24

Official Full Name: zDHHC palmitoyltransferase 24provided by HGNC

Gene Summary: Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21160 ZDHHC24 Knockout cell line (HeLa) Human ZDHHC24 1:3~1:6 Negative Online Inquiry
KO21161 ZDHHC24 Knockout cell line (HCT 116) Human ZDHHC24 1:2~1:4 Negative Online Inquiry
KO21162 ZDHHC24 Knockout cell line (HEK293) Human ZDHHC24 1:3~1:6 Negative Online Inquiry
KO21163 ZDHHC24 Knockout cell line (A549) Human ZDHHC24 1:3~1:4 Negative Online Inquiry

Background

ZDHHC24 Gene Knockout Cell Lines are genetically engineered cellular models that have had the ZDHHC24 gene specifically inactivated or deleted. This gene encodes a member of the DHHC-type zinc-finger protein family, which plays a significant role in post-translational modifications, particularly in palmitoylation processes that affect protein localization, stability, and function. The knockout of ZDHHC24 facilitates the study of its biological implications, allowing researchers to elucidate the underlying mechanisms of palmitoylation and its impact on cellular pathways.

These cell lines function by providing a robust platform for investigating the consequences of ZDHHC24 deficiency, enabling scientists to explore various physiological and pathological processes such as neurodegeneration, cancer progression, and metabolic diseases. The absence of ZDHHC24 allows researchers to determine how the lack of palmitoylation influences cellular signaling and protein interaction networks, thereby providing insight into therapeutic targets.

The scientific importance of ZDHHC24 Gene Knockout Cell Lines lies in their application in fundamental research and drug development. They offer a unique tool for screening potential drug candidates that may restore or compensate for the loss of ZDHHC24 function, aiding in the discovery of novel therapeutic approaches. Compared to traditional cell lines that express the ZDHHC24 gene, these knockout models represent a more accurate system for studying the direct effects of the gene’s absence, minimizing confounding factors and enhancing experimental reliability.

Researchers and clinicians will find these cell lines invaluable due to their specificity and the depth of analysis they facilitate. They offer a streamlined approach to answering complex biological questions and advancing personalized medicine strategies. Moreover, our company specializes in providing high-quality genetic models backed by rigorous validation and extensive expertise in the development of customized biological tools. Our commitment is to empower research and innovation with cutting-edge products like the ZDHHC24 Gene Knockout Cell Lines, designed to meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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