Home / ZBTB5 Knockout Cell Lines

ZBTB5 Knockout Cell Lines

Gene: Zbtb5

Official Full Name: zinc finger and BTB domain containing 5provided by MGI

Gene Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including cardiovascular system; genitourinary system; gut; nervous system; and skin. Orthologous to human ZBTB5 (zinc finger and BTB domain containing 5). [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32500 ZBTB5 Knockout cell line (HeLa) Human ZBTB5 1:3~1:6 Negative Online Inquiry
KO32501 ZBTB5 Knockout cell line (HCT 116) Human ZBTB5 1:2~1:4 Negative Online Inquiry
KO32502 ZBTB5 Knockout cell line (HEK293) Human ZBTB5 1:3~1:6 Negative Online Inquiry
KO32503 ZBTB5 Knockout cell line (A549) Human ZBTB5 1:3~1:4 Negative Online Inquiry

Background

Zbtb5 gene knockout cell lines are genetically engineered cellular models specifically designed to disrupt the function of the Zbtb5 gene, implicated in various cellular processes, including transcriptional regulation and cell differentiation. These knockout lines serve as powerful tools for researchers investigating the role of Zbtb5 in cellular signaling pathways, developmental biology, and potential roles in disease mechanisms, including cancer progression and autoimmune disorders.

The primary function of Zbtb5 gene knockout cell lines is to enable the systematic study of Zbtb5's biological functions by allowing researchers to observe the phenotypic changes that occur in its absence. The knockout is achieved using advanced CRISPR-Cas9 technology, which generates precise mutations within the gene, effectively silencing its expression. This mechanism permits a detailed examination of downstream effects and interactions with other molecular pathways, providing insights into its role in normal physiology as well as pathology.

Scientifically, these cell lines are invaluable for applications in both basic research and translational studies. In a research setting, they can help elucidate gene function, regulatory networks, and potential therapeutic targets. Clinically, understanding Zbtb5’s involvement in disease pathways may pave the way for developing more effective treatments tailored to specific molecular profiles in patients.

The unique advantage of Zbtb5 gene knockout cell lines lies in their specificity and ease of use. Unlike traditional knockout models that require extensive genetic manipulation of whole organisms, these lines offer rapid, reproducible results, ideal for high-throughput screening and various experimental conditions. When compared to alternative models, researchers benefit from the precise control over environmental variables and the ability to generate isogenic lines that reflect human biology.

For researchers and clinicians focusing on gene function and therapeutic development, Zbtb5 gene knockout cell lines are a vital resource that enhances experimental rigor and accelerates discovery. Our company specializes in providing high-quality, well-characterized cellular models to support innovative research endeavors, underpinned by our commitment to scientific integrity and excellence in biotechnological solutions.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.