Gene: ZBTB46
Official Full Name: zinc finger and BTB domain containing 46provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25575 | ZBTB46 Knockout cell line (HCT 116) | Human | ZBTB46 | 1:2~1:4 | Negative | Online Inquiry |
KO25576 | ZBTB46 Knockout cell line (HEK293) | Human | ZBTB46 | 1:3~1:6 | Negative | Online Inquiry |
ZBTB46 Gene Knockout Cell Lines are specialized cellular models created for the precise inactivation of the ZBTB46 gene, which encodes a transcription factor involved in various regulatory processes within the immune system. These cell lines provide invaluable tools for researchers seeking to elucidate the role of ZBTB46 in cellular mechanisms such as immune response modulation, hematopoiesis, and potentially in the pathogenesis of certain diseases.
The primary function of these knockout cell lines is to study gene function by eliminating the expression of ZBTB46 and observing the resultant phenotypic and biological changes. By utilizing CRISPR-Cas9 gene-editing technology, researchers can disrupt the ZBTB46 locus with high specificity, allowing for an assessment of the gene's roles in both normal physiology and disease states. This approach enables a deeper understanding of the gene's contribution to immune cell differentiation and function, facilitating advancements in therapeutic strategies for immune-related disorders.
In scientific research and clinical applications, ZBTB46 Gene Knockout Cell Lines are vital for paving the way in studies on autoimmunity, cancer immunology, and stem cell research. Their application is crucial in drug discovery, enabling scientists to screen for potential compounds that could restore or alter functionality lost due to ZBTB46 gene inactivation, thus creating opportunities for targeted therapies.
What sets our ZBTB46 Gene Knockout Cell Lines apart is their rigorous validation and optimization for enhanced performance compared to similar products on the market. With consistent growth characteristics and reproducible gene knockout efficiency, these cell lines achieve results that demand confidence in experimental reproducibility.
Researchers and clinicians can derive substantial value from these cell lines by gaining insight into critical biological processes affecting immune functions. Our company takes pride in its extensive expertise in gene editing and cellular models, delivering high-quality biological products that drive innovative scientific discovery and accelerate advancements in personalized medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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