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ZBTB45 Knockout Cell Lines

Gene: ZBTB45

Official Full Name: zinc finger and BTB domain containing 45provided by HGNC

Gene Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24571 ZBTB45 Knockout cell line (HeLa) Human ZBTB45 1:3~1:6 Negative Online Inquiry
KO24572 ZBTB45 Knockout cell line (HCT 116) Human ZBTB45 1:2~1:4 Negative Online Inquiry
KO24573 ZBTB45 Knockout cell line (HEK293) Human ZBTB45 1:3~1:6 Negative Online Inquiry
KO24574 ZBTB45 Knockout cell line (A549) Human ZBTB45 1:3~1:4 Negative Online Inquiry

Background

ZBTB45 Gene Knockout Cell Lines are advanced genetically modified cell lines designed to facilitate the study of the ZBTB45 (Zinc Finger and BTB Domain Containing 45) gene's function and its implications in cellular processes. This product enables scientists to investigate the gene's roles by providing a platform for examining the effects of ZBTB45 loss-of-function on various biological mechanisms such as cell differentiation, proliferation, and apoptosis, which are essential in both normative physiology and disease states.

The ZBTB45 knockout mechanism operates through CRISPR/Cas9 technology, where specific sequences of the ZBTB45 gene are disrupted, leading to the complete ablation of its expression. This precise editing allows researchers to generate isogenic control lines, ensuring that observed phenotypic changes are directly attributable to the gene knockout. As a result, these cell lines are invaluable tools in oncological research, neurobiology, and developmental studies, where ZBTB45's regulatory functions may contribute to disease pathology or cellular development.

The scientific significance of ZBTB45 Gene Knockout Cell Lines is underscored by their broad applications in both fundamental research and clinical settings. They can be utilized in drug discovery, understanding gene interactions, and elucidating pathways involved in diseases like cancer, autoimmune disorders, and neurological conditions. Furthermore, the ability to generate multiple cell types from a single ZBTB45 knockout line enhances their utility in diverse experimental setups.

Unique to our offering, these cell lines come with rigorous quality control, ensuring high transfection efficiency, reproducibility, and consistent results across experiments. Unlike similar products on the market, our ZBTB45 Gene Knockout Cell Lines are produced under stringent ethical guidelines and comply with international standards for biological research, making them a trusted choice for researchers.

For scientists and clinicians, the value of ZBTB45 Gene Knockout Cell Lines lies in their capacity to accelerate discovery and innovation, paving the way for breakthroughs in understanding disease mechanisms and therapeutic development. Our company boasts a strong foundation in genomic research and a commitment to providing high-quality biological tools that meet the evolving needs of the scientific community, making our product an essential resource for advancing your research objectives.

Please note that all services are for research use only. Not intended for any clinical use.

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