Gene: ZBED2
Official Full Name: zinc finger BED-type containing 2provided by HGNC
Gene Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of keratinocyte differentiation. Predicted to be located in chromatin. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12510 | ZBED2 Knockout cell line (HeLa) | Human | ZBED2 | 1:3~1:6 | Negative | Online Inquiry |
KO12511 | ZBED2 Knockout cell line (HCT 116) | Human | ZBED2 | 1:2~1:4 | Negative | Online Inquiry |
KO12512 | ZBED2 Knockout cell line (A549) | Human | ZBED2 | 1:3~1:4 | Negative | Online Inquiry |
ZBED2 Gene Knockout Cell Lines are engineered cellular models designed to facilitate the study of the ZBED2 gene, which plays a crucial role in various biological processes, including cellular differentiation and gene expression regulation. Through the use of CRISPR-Cas9 technology, these cell lines have been precisely modified to exhibit a complete knockout of the ZBED2 gene, allowing researchers to investigate the consequent phenotypic and molecular changes resulting from this genetic alteration.
The primary function of ZBED2 Gene Knockout Cell Lines lies in providing a reliable platform for studying the effects of ZBED2 deficiency on cellular behavior. By eliminating this gene, researchers can observe alterations in signaling pathways, transcriptional regulation, and cellular function. This is particularly relevant in the fields of cancer research, developmental biology, and gene therapy, where understanding the role of ZBED2 is pivotal.
Scientifically, the ZBED2 gene has been implicated in tumorigenesis and various disease states, making it a target for therapeutic interventions. In clinical applications, these knockout cell lines serve as invaluable tools for drug screening and biomarker discovery, enhancing our understanding of disease mechanisms and facilitating the development of targeted therapies.
What sets ZBED2 Gene Knockout Cell Lines apart from alternative models is their high specificity and reproducibility, which minimize off-target effects often associated with other gene-editing methods. The availability of these cell lines provides researchers with a robust and validated system for comprehensive studies without the complexities of traditional knockout strategies.
For researchers and clinicians, the ability to access ZBED2 Gene Knockout Cell Lines is a game-changer, offering a unique window into the molecular underpinnings of diseases related to ZBED2 dysfunction. Our company is dedicated to advancing the life sciences, and our expertise in gene editing technologies ensures that we provide high-quality, state-of-the-art products that empower research and innovation in biological sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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