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YES1 Knockout Cell Lines

Gene: YES1

Official Full Name: YES proto-oncogene 1, Src family tyrosine kinaseprovided by HGNC

Gene Summary: This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05776 YES1 Knockout cell line (HeLa) Human YES1 1:3~1:6 Negative Online Inquiry
KO05777 YES1 Knockout cell line (HCT 116) Human YES1 1:2~1:4 Negative Online Inquiry
KO05778 YES1 Knockout cell line (HEK293) Human YES1 1:3~1:6 Negative Online Inquiry
KO05779 YES1 Knockout cell line (A549) Human YES1 1:3~1:4 Negative Online Inquiry

Background

YES1 Gene Knockout Cell Lines are genetically engineered cell lines that specifically lack the YES1 gene, which encodes a non-receptor tyrosine kinase involved in a variety of cellular processes, including growth factor signaling and cell proliferation. By eliminating YES1 expression, these cell lines create a powerful tool for researchers to investigate the role of this gene in cellular signaling, oncogenesis, and response to pharmacological agents.

The key function of YES1 Gene Knockout Cell Lines lies in their ability to serve as a model for studying the functional consequences of YES1 depletion. Researchers can utilize these cell lines to assess changes in cellular behavior, including alterations in signaling pathways and metabolic processes. This knockout model enables the dissection of YES1's role in specific conditions, such as cancer and other diseases, by providing insights into how the absence of this kinase affects cell survival, growth, and interaction with other cellular proteins.

Scientific integrity in studying gene functions is paramount, and these knockout cell lines facilitate robust and reproducible research data. In clinical settings, the YES1 Gene Knockout can help validate potential therapeutic targets, allowing for the advancement of personalized medicine by identifying specific vulnerabilities in cancer cells. The findings from such research may lead to novel treatment strategies aimed at inhibiting YES1-related pathways.

When compared to alternative models, YES1 Gene Knockout Cell Lines offer a direct and targeted approach to gene disruption, providing clearer, more precise results. This specificity reduces genetic background noise that can confound results, leading to higher confidence in data interpretation.

The value of YES1 Gene Knockout Cell Lines extends beyond mere research utility—they represent a step forward in understanding complex biological mechanisms. Researchers and clinicians can rely on this product to enhance their experimental designs and ultimately accelerate the pace of discovery in life sciences.

Our company specializes in providing high-quality biological products designed to empower scientific exploration. With an unwavering commitment to innovation and excellence, we ensure our offerings meet the rigorous standards required for cutting-edge research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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