Gene: YAF2
Official Full Name: YY1 associated factor 2provided by HGNC
Gene Summary: This gene encodes a zinc finger containing protein that functions in the regulation of transcription. This protein was identified as an interacting partner of transcriptional repressor protein Yy1, and also interacts with other transcriptional regulators, including Myc and Polycomb. This protein can promote proteolysis of Yy1. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Feb 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32249 | YAF2 Knockout cell line (HeLa) | Human | YAF2 | 1:3~1:6 | Negative | Online Inquiry |
KO32250 | YAF2 Knockout cell line (HCT 116) | Human | YAF2 | 1:2~1:4 | Negative | Online Inquiry |
KO32251 | YAF2 Knockout cell line (HEK293) | Human | YAF2 | 1:3~1:6 | Negative | Online Inquiry |
KO32252 | YAF2 Knockout cell line (A549) | Human | YAF2 | 1:3~1:4 | Negative | Online Inquiry |
YAF2 Gene Knockout Cell Lines are specialized biological tools designed for advanced genetic research, particularly in the field of gene function analysis. These cell lines are created by employing CRISPR-Cas9 technology, which allows for precise deletions or modifications of the YAF2 gene, enabling researchers to study its implications in cellular processes, signaling pathways, and disease states.
The primary mechanism of action involves the targeted disruption of the YAF2 gene, resulting in a loss of function that elucidates the role of this gene in various biological contexts. Researchers utilize these knockout cell lines to investigate alterations in gene expression profiles, cellular behavior, and response to stimuli, facilitating a deeper understanding of the YAF2 gene's involvement in processes such as apoptosis, differentiation, and cancer progression.
The significance of YAF2 Gene Knockout Cell Lines extends into both research and clinical applications. In research settings, these cell lines aid in functional genomics studies, enabling scientists to dissect the molecular underpinnings of diseases and potential therapeutic targets. Clinically, insights gained from these knockout models can illuminate pathways for developing novel treatments, particularly in oncology, where understanding the tumor microenvironment and gene interactions is crucial.
What sets our YAF2 Gene Knockout Cell Lines apart from alternatives is their unparalleled specificity and validation, backed by thorough genomic analysis to confirm the efficacy of the knockouts. Our products are also characterized by consistency in growth and maintenance, ensuring that researchers can replicate experiments reliably.
For researchers and clinicians alike, investing in YAF2 Gene Knockout Cell Lines represents a strategic advantage in pioneering studies that can lead to breakthroughs in therapeutic development. Our commitment to scientific excellence is exemplified in our capabilities in cell line development, ensuring that each product meets the highest standards for quality and performance, thereby supporting your research agenda effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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