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XKR8 Knockout Cell Lines

Gene: XKR8

Official Full Name: XK related 8provided by HGNC

Gene Summary: Enables phospholipid scramblase activity. Involved in engulfment of apoptotic cell; phosphatidylserine exposure on apoptotic cell surface; and positive regulation of myoblast differentiation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12567 XKR8 Knockout cell line (HeLa) Human XKR8 1:3~1:6 Negative Online Inquiry
KO12568 XKR8 Knockout cell line (HCT 116) Human XKR8 1:2~1:4 Negative Online Inquiry
KO12569 XKR8 Knockout cell line (HEK293) Human XKR8 1:3~1:6 Negative Online Inquiry
KO12570 XKR8 Knockout cell line (A549) Human XKR8 1:3~1:4 Negative Online Inquiry

Background

XKR8 Gene Knockout Cell Lines are specialized cellular models engineered to disrupt the expression of the XKR8 gene, a member of the K+ transport family, which plays a crucial role in cellular processes such as ion homeostasis, cell volume regulation, and apoptosis. These cell lines are valuable tools in the fields of molecular biology and genetics, providing researchers with the ability to study the specific functions of the XKR8 gene and its protein product in cellular contexts.

The key function of XKR8 Gene Knockout Cell Lines lies in their capacity to facilitate detailed investigations into the physiological and pathological roles of the XKR8 gene. By utilizing CRISPR/Cas9 technology, these cell lines permit targeted mutations that effectively silence gene expression. This strategic manipulation allows scientists to observe the resultant phenotypic changes, thereby elucidating the molecular pathways influenced by XKR8, particularly in the contexts of cancer research, neurobiology, and immune responses.

The scientific importance of XKR8 Gene Knockout Cell Lines extends to both basic research and clinical applications. In research settings, these models are essential for exploring gene function and regulatory mechanisms, while in clinical environments, they hold potential for therapeutic strategies that target specific disease mechanisms linked to XKR8 dysregulation.

What sets our XKR8 Gene Knockout Cell Lines apart from alternatives is their high efficiency and specificity in gene editing, ensuring reliable results. These lines have been rigorously validated for consistency and robustness, making them ideal for reproducible experimental outcomes. Furthermore, our dedication to quality control and user support enhances the researchers' experience, allowing them to focus on their investigative goals without compromising on the accuracy of their findings.

In conclusion, XKR8 Gene Knockout Cell Lines represent an invaluable asset for researchers and clinicians alike. With our extensive experience in biological products and a commitment to advancing scientific knowledge, we provide tools that empower discoveries in cellular biology and beyond, facilitating groundbreaking research that ultimately improves human health.

Please note that all services are for research use only. Not intended for any clinical use.

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