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XK Knockout Cell Lines

Gene: XK

Official Full Name: X-linked Kx blood group antigen, Kell and VPS13A binding proteinprovided by HGNC

Gene Summary: This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34797 XK Knockout cell line (HeLa) Human XK 1:3~1:6 Negative Online Inquiry
KO34798 XK Knockout cell line (HCT 116) Human XK 1:2~1:4 Negative Online Inquiry
KO34799 XK Knockout cell line (HEK293) Human XK 1:3~1:6 Negative Online Inquiry
KO34800 XK Knockout cell line (A549) Human XK 1:3~1:4 Negative Online Inquiry

Background

XK Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to facilitate research into gene function and regulation by utilizing CRISPR-Cas9 technology for targeted gene disruption. These cell lines are derived from various species and cell types to provide a versatile platform for investigating the biological roles of genes implicated in diverse processes such as development, metabolism, and disease pathology. The key mechanism underlying these knockout cell lines involves the precise deletion of a target gene, which allows researchers to study the resulting phenotypic changes and potential compensatory mechanisms that may arise due to the gene's inactivation.

The scientific importance of XK Gene Knockout Cell Lines lies in their application across numerous research disciplines, including cancer biology, pharmacology, and immunology. By utilizing these models, researchers can gain critical insights into gene function and its contribution to disease, leading to the identification of novel therapeutic targets. Additionally, XK Gene Knockout Cell Lines serve as invaluable tools for validating gene targets in drug discovery and functional genomics, thereby enhancing translational research efforts.

One of the primary advantages of XK Gene Knockout Cell Lines is their high specificity and efficiency in gene disruption compared to traditional methods such as RNA interference or nongene-editing techniques. This results in more reliable and reproducible research outcomes. Furthermore, our cell lines are extensively validated and characterized, ensuring consistent performance across various experiments.

The unique selling points of XK Gene Knockout Cell Lines include their extensive versatility, ease of use, and the comprehensive support provided by our expert team. We are committed to delivering quality products that empower researchers and clinicians alike to push the boundaries of scientific discovery. Our expertise in genetic engineering and cellular biology uniquely positions us to provide exceptional solutions tailored to meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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