Gene: WWC2
Official Full Name: WW and C2 domain containing 2provided by HGNC
Gene Summary: This gene encodes a member of the WW-and-C2-domain-containing family of proteins. Members of this family have two N-terminal WW domains that mediate binding to target proteins harboring L/PPxY motifs, an internal C2 domain for membrane association, and C-terminal alpha protein kinase C binding sites and class III PDZ domain-interaction motifs. Proteins of this family are able to form homo- and heterodimers and to modulate hippo pathway signaling. [provided by RefSeq, Sep 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12579 | WWC2 Knockout cell line (HeLa) | Human | WWC2 | 1:3~1:6 | Negative | Online Inquiry |
KO12580 | WWC2 Knockout cell line (HCT 116) | Human | WWC2 | 1:2~1:4 | Negative | Online Inquiry |
KO12581 | WWC2 Knockout cell line (HEK293) | Human | WWC2 | 1:3~1:6 | Negative | Online Inquiry |
KO12582 | WWC2 Knockout cell line (A549) | Human | WWC2 | 1:3~1:4 | Negative | Online Inquiry |
WWC2 Gene Knockout Cell Lines are a cutting-edge tool designed for researchers aiming to investigate the functional roles of the WWC2 gene in various biological processes. These cell lines are engineered to possess a complete knockout of the WWC2 gene, which plays a significant role in cellular signaling pathways, cell adhesion, and the regulation of cellular differentiation. By removing this gene, scientists can explore its implications in disease mechanisms, particularly in cancer biology and developmental syndromes.
The primary mechanism by which the WWC2 Gene Knockout Cell Lines operate involves the disruption of WWC2 expression, allowing researchers to observe the phenotypic consequences and alterations in cellular behavior. This knockout model is particularly valuable for studying pathways related to cell migration, proliferation, and apoptosis, providing a clearer understanding of how WWC2 influences cellular dynamics.
In terms of scientific importance, these cell lines have broad applications in both basic and translational research settings. They enable the dissection of complex signaling networks and facilitate the identification of potential therapeutic targets for diseases where WWC2 is implicated. Further, they aid in preclinical drug development by providing a reliable model to test the efficacy of novel therapeutics.
Compared to alternative methods such as transient transfection assays or RNA interference, the WWC2 Gene Knockout Cell Lines offer a more stable and permanent solution for gene inactivation. This stability enhances the reproducibility of experiments and the reliability of results, making it easier for researchers to achieve consistent outcomes and comparisons across studies.
By offering high-quality, validated WWC2 Gene Knockout Cell Lines, we empower researchers and clinicians to gain deeper insights into gene function and its role in various pathologies. Our team combines extensive expertise in cellular biology and genetic engineering, ensuring that our products meet the highest scientific standards and serve as invaluable resources in the pursuit of biomedical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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