Gene: WRAP73
Official Full Name: WD repeat containing, antisense to TP73provided by HGNC
Gene Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Studies of the related mouse protein suggest that the encoded protein may play a role in the process of ossification. [provided by RefSeq, Mar 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23640 | WRAP73 Knockout cell line (HeLa) | Human | WRAP73 | 1:3~1:6 | Negative | Online Inquiry |
KO23641 | WRAP73 Knockout cell line (HCT 116) | Human | WRAP73 | 1:2~1:4 | Negative | Online Inquiry |
KO23642 | WRAP73 Knockout cell line (HEK293) | Human | WRAP73 | 1:3~1:6 | Negative | Online Inquiry |
KO23643 | WRAP73 Knockout cell line (A549) | Human | WRAP73 | 1:3~1:4 | Negative | Online Inquiry |
WRAP73 Gene Knockout Cell Lines are meticulously engineered cellular models designed to study the functional roles of the WRAP73 gene in various biological processes and disease mechanisms. Utilizing advanced CRISPR-Cas9 gene editing technology, these cell lines enable researchers to effectively silence the WRAP73 gene, allowing for the precise investigation of its contributions to cellular pathways and its implications in conditions such as cancer progression, immune response, and tissue regeneration.
The primary mechanism involves the introduction of targeted genomic mutations within the WRAP73 locus, leading to a significant decrease or complete loss of gene expression. This knockout approach facilitates the analysis of phenotypic changes in cellular behavior, signaling pathways, and transcriptomic profiles, providing critical insights into how WRAP73 influences cell growth, differentiation, and apoptosis.
The scientific importance of WRAP73 Gene Knockout Cell Lines extends to both basic research and clinical applications. They serve as valuable tools for identifying novel therapeutic targets and biomarkers, contributing to drug discovery processes and the development of tailored treatment strategies. Furthermore, understanding the role of WRAP73 could pave the way for advancements in regenerative medicine and cancer therapies.
Compared to alternative models, WRAP73 Gene Knockout Cell Lines offer superior specificity and efficiency in gene disruption, which significantly enhances the reliability of experimental results. Users benefit from the ready-to-use nature of these cell lines, ensuring seamless integration into research workflows while saving valuable time typically spent on preliminary optimization.
In conclusion, WRAP73 Gene Knockout Cell Lines represent an indispensable resource for researchers and clinicians seeking to unravel complex gene functions in health and disease. Our company is committed to providing high-quality biological products backed by robust scientific expertise, ensuring that researchers acquire reliable tools to advance their work effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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