Gene: WNT9A
Official Full Name: Wnt family member 9Aprovided by HGNC
Gene Summary: The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is expressed in gastric cancer cell lines. The protein encoded by this gene shows 75% amino acid identity to chicken Wnt14, which has been shown to play a central role in initiating synovial joint formation in the chick limb. This gene is clustered with another family member, WNT3A, in the chromosome 1q42 region. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11613 | WNT9A Knockout cell line (HeLa) | Human | WNT9A | 1:3~1:6 | Negative | Online Inquiry |
KO11614 | WNT9A Knockout cell line (HCT 116) | Human | WNT9A | 1:2~1:4 | Negative | Online Inquiry |
KO11615 | WNT9A Knockout cell line (A549) | Human | WNT9A | 1:3~1:4 | Negative | Online Inquiry |
WNT9A Gene Knockout Cell Lines are genetically engineered cell lines that have had the WNT9A gene inactivated, providing a powerful tool for studying the role of this critical gene in cellular processes. The WNT9A gene is known to play a significant role in the Wnt signaling pathway, which is essential for various developmental processes and the regulation of cell proliferation, differentiation, and stem cell maintenance. By knocking out this gene, researchers can observe the resultant phenotypic changes, enabling a deeper understanding of WNT9A’s specific contributions to various biological functions.
The key mechanism of action involving these knockout cell lines lies in their ability to mimic disease states or developmental defects that arise from altered Wnt signaling. Researchers can utilize these cell lines to investigate the nuances of WNT9A’s involvement in pathways related to cancer, stem cell biology, and tissue regeneration. The applications extend beyond basic research to translational contexts, where understanding WNT9A may open avenues for developing targeted therapies or novel biomarkers.
One of the distinctive advantages of our WNT9A Gene Knockout Cell Lines is their high efficiency and specificity in gene inactivation, reducing off-target effects commonly associated with traditional gene editing methods. Compared to other gene editing techniques, our cell lines are designed to facilitate reproducible and versatile experimental setups, benefiting both in vitro and in vivo studies.
The value of WNT9A Gene Knockout Cell Lines to researchers and clinicians cannot be overstated. By leveraging these cell lines, scientists can elucidate the mechanisms of diseases linked to aberrant WNT signaling, potentially paving the way for innovative therapeutic strategies. Furthermore, our commitment to quality ensures that each cell line comes with detailed characterization data and robust support, empowering users to maximize their research outcomes.
As a leader in the field of biological products, our company specializes in providing advanced research tools that enhance scientific exploration and discovery. Our expertise in genetic engineering and commitment to quality make us a trusted partner for laboratories seeking to tackle the complexities of cellular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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