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WNT11 Knockout Cell Lines

Gene: WNT11

Official Full Name: Wnt family member 11provided by HGNC

Gene Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome. [provided by RefSeq, Jul 2008]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09107 WNT11 Knockout cell line (HEK293) Human WNT11 1:3~1:6 Negative Online Inquiry

Background

WNT11 Gene Knockout Cell Lines represent a significant advancement in molecular biology research, specifically designed to study the role of the Wnt signaling pathway in various biological processes. These cell lines are engineered to have the WNT11 gene selectively disrupted, allowing researchers to investigate the functional implications of WNT11 deletion in cellular functions such as proliferation, differentiation, and migration. The Wnt signaling cascade, a pivotal regulator of embryonic development and tissue homeostasis, has been implicated in numerous disease states, including cancer and degenerative disorders; thus, these knockout cell lines are invaluable tools for understanding disease mechanisms.

The key function of WNT11 Gene Knockout Cell Lines lies in their ability to mimic natural gene knockout conditions, enabling scientists to observe the resultant phenotypic changes and alterations in downstream signaling pathways. By eliminating WNT11 expression, researchers can elucidate its specific roles and contribution in various contexts, particularly in developmental biology and cancer research. These cell lines can be used to assess the impact of WNT11 on cell behavior, enabling comprehensive studies on drug responses and cellular interactions.

In research settings, the scientific importance of these knockout cell lines cannot be overstated. They provide essential insights into the Wnt pathway's contribution to oncogenesis and normal physiology, which could lead to the discovery of novel therapeutic targets. Clinically, understanding the implications of WNT11 can pave the way for developing strategies to counteract the aberrations seen in patients suffering from Wnt-pathway-related diseases.

What sets our WNT11 Gene Knockout Cell Lines apart from alternative products is their rigorous validation process, ensuring high fidelity in gene knockout efficiency and stable expression of other genetic factors. This reliability enables reproducible results, giving researchers confidence in their findings. Additionally, our cell lines come with extensive documentation and user support, facilitating straightforward integration into existing research protocols.

For researchers and clinicians focused on elucidating the complexities of signaling pathways in health and disease, the WNT11 Gene Knockout Cell Lines offer a robust and reliable tool. Our commitment to high-quality biological products stems from our extensive expertise and dedication to advancing scientific discovery, ensuring researchers have access to the best resources for their groundbreaking work.

Please note that all services are for research use only. Not intended for any clinical use.

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