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WNT10B Knockout Cell Lines

Gene: WNT10B

Official Full Name: Wnt family member 10Bprovided by HGNC

Gene Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11631 WNT10B Knockout cell line (HeLa) Human WNT10B 1:3~1:6 Negative Online Inquiry
KO11632 WNT10B Knockout cell line (HCT 116) Human WNT10B 1:2~1:4 Negative Online Inquiry
KO11633 WNT10B Knockout cell line (HEK293) Human WNT10B 1:3~1:6 Negative Online Inquiry
KO11634 WNT10B Knockout cell line (A549) Human WNT10B 1:3~1:4 Negative Online Inquiry

Background

WNT10B Gene Knockout Cell Lines are engineered cellular models specifically designed to study the biological functions associated with the WNT10B gene, a member of the Wnt signaling pathway known for its roles in cellular processes such as proliferation, differentiation, and oncogenesis. These cell lines have been meticulously developed through CRISPR-Cas9 technology, ensuring precise and heritable gene modifications that allow researchers to observe the phenotypic and molecular consequences of WNT10B loss of function.

The primary mechanism of action involves the targeted disruption of the WNT10B gene, which leads to the downstream inhibition of Wnt signaling pathways. This alteration provides invaluable insights into the role of WNT10B in various physiological and pathological contexts, such as development, bone metabolism, and cancer progression. By utilizing these knockout cell lines, researchers can explore the impact of WNT signaling on cellular behavior and investigate potential therapeutic targets for diseases linked to dysregulated Wnt signaling.

The scientific relevance of WNT10B Gene Knockout Cell Lines extends to both basic and applied research, with applications in drug discovery, cancer biology, and regenerative medicine. These cell lines facilitate the elucidation of molecular pathways and provide a platform for testing the efficacy of new pharmacological agents aimed at modulating Wnt signaling.

What sets WNT10B Gene Knockout Cell Lines apart from alternative models are their specificity, reliability, and the reproducibility of results. They are expertly curated to minimize genetic background noise, thereby allowing for clearer interpretation of experimental data. Furthermore, these cell lines are compatible with a variety of assays, including high-throughput screening, making them versatile tools for diverse research applications.

For researchers and clinicians dedicated to advancing our understanding of Wnt signaling and its implications in health and disease, WNT10B Gene Knockout Cell Lines offer a unique and valuable asset. With a commitment to precision and quality, our company proudly provides these advanced biological products, backed by extensive expertise in genetic engineering and cellular biology research.

Please note that all services are for research use only. Not intended for any clinical use.

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