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WDSUB1 Knockout Cell Lines

Gene: WDSUB1

Official Full Name: WD repeat, sterile alpha motif and U-box domain containing 1provided by HGNC

Gene Summary: Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21950 WDSUB1 Knockout cell line (HeLa) Human WDSUB1 1:3~1:6 Negative Online Inquiry
KO21951 WDSUB1 Knockout cell line (HCT 116) Human WDSUB1 1:2~1:4 Negative Online Inquiry
KO21952 WDSUB1 Knockout cell line (HEK293) Human WDSUB1 1:3~1:6 Negative Online Inquiry
KO21953 WDSUB1 Knockout cell line (A549) Human WDSUB1 1:3~1:4 Negative Online Inquiry

Background

WDSUB1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the WDSUB1 gene, a pivotal gene implicated in various biological processes, including cell proliferation and apoptosis. These knockout cell lines serve as a powerful tool for researchers aiming to elucidate the role of WDSUB1 in cellular functions and its potential involvement in disease mechanisms.

The primary mechanism of action for WDSUB1 Gene Knockout Cell Lines lies in the CRISPR/Cas9 gene-editing technology, which ensures precise deletion of the WDSUB1 gene, leading to a complete absence of its protein product. This enables in-depth investigations into the gene's contribution to cellular pathways and validations of related hypotheses. Researchers can reliably observe phenotypic changes, allowing for the exploration of gene function in various biological contexts, including cancer research, developmental biology, and drug response assays.

The scientific significance of these cell lines is manifold. They are invaluable in assessing the impact of WDSUB1 loss on cellular processes and can significantly aid in drug discovery and the development of targeted therapeutics. In the clinical setting, understanding the role of WDSUB1 can shed light on its potential as a biomarker or therapeutic target, thus facilitating advancements in precision medicine.

WDSUB1 Gene Knockout Cell Lines stand out due to their high specificity, reproducibility, and ability to be utilized in various experimental designs compared to less targeted approaches like RNA interference or traditional knockout techniques. Their streamlined generation process and a robust validation profile enhance their reliability for cutting-edge research applications.

This product is indispensable for researchers and clinicians seeking to deepen their understanding of gene functions in health and disease, helping them bridge the gap between basic research and clinical application. Our company prides itself on its expertise in gene editing technologies and commitment to providing high-quality, reliable biological products that empower scientific innovation and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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