Gene: WDR24
Official Full Name: WD repeat domain 24provided by HGNC
Gene Summary: Enables ubiquitin protein ligase activity. Involved in several processes, including cellular response to amino acid starvation; positive regulation of TORC1 signaling; and protein K6-linked ubiquitination. Located in cytosol and lysosomal membrane. Part of GATOR2 complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00113 | WDR24 Knockout cell line (HEK293) | Human | WDR24 | 1:3~1:6 | Negative | Online Inquiry |
KO09189 | WDR24 Knockout cell line (HeLa) | Human | WDR24 | 1:3~1:6 | Negative | Online Inquiry |
KO09190 | WDR24 Knockout cell line (HCT 116) | Human | WDR24 | 1:2~1:4 | Negative | Online Inquiry |
WDR24 Gene Knockout Cell Lines are specifically engineered cellular models in which the WDR24 gene has been systematically disrupted through the use of CRISPR/Cas9 technology. This innovative approach to gene editing allows researchers to investigate the biological role of WDR24 in various cellular processes, including cell proliferation, differentiation, and apoptosis. By knocking out the WDR24 gene, scientists can create a controlled environment to study the downstream effects on gene expression and protein function, providing valuable insights into its contribution to cellular homeostasis and disease mechanisms.
Key functions of the WDR24 Gene Knockout Cell Lines include enabling the assessment of various signaling pathways that may be impacted by the absence of WDR24, facilitating the dissection of its potential roles in oncogenesis, inflammation, and immune responses. Moreover, these cell lines serve as essential tools for validating pharmacological targets and exploring therapeutic interventions in cancer and autoimmune diseases. Their utility extends across both academic and industrial research settings, where they can assist in the discovery of novel drug candidates and biomolecular interactions.
One of the primary advantages of utilizing WDR24 Gene Knockout Cell Lines is the precision achieved through targeted gene editing. Unlike traditional knockout methods that may produce off-target effects, the CRISPR/Cas9 system provides a high specificity and efficiency, significantly enhancing the reproducibility of experimental results. Furthermore, researchers can easily compare the behavior of WDR24 knockout cells to wild-type controls, delivering clear insights into gene function.
The value of these cell lines to researchers and clinicians lies in their capacity to improve the understanding of complex pathophysiological processes and the development of novel therapeutic strategies. By elucidating the role of WDR24 in health and disease, these tools can guide interventions that may lead to improved treatment outcomes.
At [Company Name], we specialize in providing advanced genetic engineering solutions tailored to the needs of researchers and clinicians. Our WDR24 Gene Knockout Cell Lines epitomize our commitment to cutting-edge science and our dedication to supporting groundbreaking research initiatives.
Please note that all services are for research use only. Not intended for any clinical use.
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