Gene: WDR20
Official Full Name: WD repeat domain 20provided by HGNC
Gene Summary: This gene encodes a WD repeat-containing protein that functions to preserve and regulate the activity of the USP12-UAF1 deubiquitinating enzyme complex. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23348 | WDR20 Knockout cell line (HeLa) | Human | WDR20 | 1:3~1:6 | Negative | Online Inquiry |
KO23349 | WDR20 Knockout cell line (HCT 116) | Human | WDR20 | 1:2~1:4 | Negative | Online Inquiry |
KO23350 | WDR20 Knockout cell line (HEK293) | Human | WDR20 | 1:3~1:6 | Negative | Online Inquiry |
KO23351 | WDR20 Knockout cell line (A549) | Human | WDR20 | 1:3~1:4 | Negative | Online Inquiry |
WDR20 Gene Knockout Cell Lines are precisely engineered cellular models that lack the expression of the WDR20 gene, a crucial component involved in multiple biological processes, including cellular signaling and protein interactions. This innovative product utilizes CRISPR/Cas9 technology for the targeted disruption of the WDR20 gene, resulting in a robust tool for researchers looking to elucidate the gene's role in various pathological conditions or cellular pathways.
The WDR20 knockout cell lines function by providing a controlled experimental setup to study the consequences of WDR20 loss on cellular functions such as proliferation, apoptosis, and response to stress stimuli. By comparing these knockout lines to their wild-type counterparts, researchers can gain insights into the molecular mechanisms underlying diseases, such as cancer, where WDR20 has been implicated.
Scientifically, the significance of these knockout cell lines lies in their application in both fundamental research and clinical settings. They serve as valuable models for drug screening, biomarker discovery, and the exploration of gene function in human disease mechanisms. Furthermore, researchers can utilize these cell lines for high-throughput assays, providing a streamlined approach to gathering data on WDR20's biological effects.
The advantages of WDR20 Gene Knockout Cell Lines over alternative options include their high specificity and efficiency, which ensure that only the desired genetic alteration has occurred, reducing the risk of off-target effects often seen with less precise gene-editing methods. Additionally, these cell lines are backed by thorough characterization and validation, ensuring reliability in experimental outcomes.
For researchers and clinicians, the value of the WDR20 Gene Knockout Cell Lines is evident in their ability to provide clear, reproducible results that enhance the understanding of gene functionality and its potential as a therapeutic target. By utilizing these specialized models, studies can yield insights that are pivotal for the development of novel treatments.
Our company prides itself on providing high-quality biological products, leveraging years of expertise in gene editing and cellular model development to support the scientific community in advancing biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.