Gene: WDFY3
Official Full Name: WD repeat and FYVE domain containing 3provided by HGNC
Gene Summary: This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. [provided by RefSeq, May 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30041 | WDFY3 Knockout cell line (HeLa) | Human | WDFY3 | 1:3~1:6 | Negative | Online Inquiry |
KO30042 | WDFY3 Knockout cell line (HCT 116) | Human | WDFY3 | 1:2~1:4 | Negative | Online Inquiry |
KO30043 | WDFY3 Knockout cell line (HEK293) | Human | WDFY3 | 1:3~1:6 | Negative | Online Inquiry |
KO30044 | WDFY3 Knockout cell line (A549) | Human | WDFY3 | 1:3~1:4 | Negative | Online Inquiry |
WDFY3 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to eliminate the expression of the WDFY3 gene, a critical component known to play a significant role in various cellular processes, such as immune response and cellular signaling. By employing CRISPR/Cas9 gene-editing technology, these cell lines provide a valuable tool for researchers aiming to dissect the specific function and pathological implications of WDFY3 in a range of biological contexts.
The functionality of the WDFY3 Gene Knockout Cell Lines lies in their ability to mimic gene loss-of-function scenarios, enabling scientists to investigate the resultant phenotypic consequences. This allows for detailed examination of cellular pathways, interaction networks, and potential therapeutic targets that may be influenced by WDFY3. Given that aberrant expression of WDFY3 has been implicated in diseases such as cancer and autoimmune disorders, these knockout lines facilitate critical research that can lead to novel interventions.
One of the most significant advantages of WDFY3 Gene Knockout Cell Lines is their specificity and reproducibility. Unlike broad-spectrum inhibitors or nonspecific genetic modifications, these cell lines provide a precise knockout model that allows for clear attribution of observed biological effects to the absence of WDFY3. Researchers can trust that the data derived from these models will yield more reliable insights, enhancing the quality of research findings.
The value proposition of WDFY3 Gene Knockout Cell Lines is clear: they empower researchers and clinicians with the ability to perform high-quality experimental assessments of genetic function and disease mechanisms. Furthermore, they support the development of targeted therapeutic approaches, potentially transforming the landscape of treatment options available for related conditions.
Our company stands at the forefront of genetic engineering, leveraging advanced technology and deep scientific expertise to provide high-quality biological products such as WDFY3 Gene Knockout Cell Lines. We are committed to supporting the scientific community's quest for knowledge and innovation through our dependable, state-of-the-art tools.
Please note that all services are for research use only. Not intended for any clinical use.
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