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WDFY2 Knockout Cell Lines

Gene: WDFY2

Official Full Name: WD repeat and FYVE domain containing 2provided by HGNC

Gene Summary: This gene encodes a protein that contains two WD domains and an FYVE zinc finger region. The function of this gene is unknown. An alternatively spliced transcript variant of this gene may exist. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30578 WDFY2 Knockout cell line (HeLa) Human WDFY2 1:3~1:6 Negative Online Inquiry
KO30579 WDFY2 Knockout cell line (HCT 116) Human WDFY2 1:2~1:4 Negative Online Inquiry
KO30580 WDFY2 Knockout cell line (HEK293) Human WDFY2 1:3~1:6 Negative Online Inquiry
KO30581 WDFY2 Knockout cell line (A549) Human WDFY2 1:3~1:4 Negative Online Inquiry

Background

WDFY2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the WDFY2 gene, which encodes a protein implicated in various biological processes, including autophagy and immune responses. These knockout cell lines are indispensable tools for researchers aiming to elucidate the functional roles of WDFY2 in cellular pathways and its contributions to disease mechanisms.

The primary function of WDFY2 Gene Knockout Cell Lines involves facilitating in-depth studies of WDFY2-dependent signaling pathways. By removing the WDFY2 gene, researchers can observe the resultant phenotypic changes and assess alterations in cellular functions such as macrophage signaling, autophagosome formation, and potential implications in diseases like cancer and autoimmunity. The knockout technique is often achieved through CRISPR/Cas9 technology, ensuring precise gene editing and reliable experimental outcomes.

The scientific importance of these cell lines extends to both basic and translational research settings. They provide critical insights into how WDFY2 regulates immune cell activation and homeostasis, which is valuable in developing targeted therapies for conditions where autophagy is dysregulated. They are also pivotal for drug discovery and can serve as platforms for testing novel therapeutic agents.

Compared to alternative systems, WDFY2 Gene Knockout Cell Lines offer distinct advantages, such as a stable genotype, reproducibility, and the ability to create isogenic models that eliminate confounding variables. This specificity is crucial in delivering clear, concise data, thus enhancing the rigor of research findings.

Researchers and clinicians invested in cellular signaling, disease mechanisms, or therapeutic development will find great value in these knockout cell lines, as they allow for precise interrogation of biological processes. Our company prides itself on providing high-quality biological products tailored to meet the evolving needs of the scientific community. With expertise in genetic engineering and a commitment to innovation, we strive to empower your research efforts with reliable, effective tools.

Please note that all services are for research use only. Not intended for any clinical use.

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