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VWDE Knockout Cell Lines

Gene: VWDE

Official Full Name: von Willebrand factor D and EGF domainsprovided by HGNC

Gene Summary: Predicted to enable signaling receptor binding activity. Predicted to be active in cell surface and extracellular region. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27356 VWDE Knockout cell line (HeLa) Human VWDE 1:3~1:6 Negative Online Inquiry
KO27357 VWDE Knockout cell line (HCT 116) Human VWDE 1:2~1:4 Negative Online Inquiry
KO27358 VWDE Knockout cell line (HEK293) Human VWDE 1:3~1:6 Negative Online Inquiry
KO27359 VWDE Knockout cell line (A549) Human VWDE 1:3~1:4 Negative Online Inquiry

Background

VWDE Gene Knockout Cell Lines are advanced cellular models specifically engineered to target and inactivate the VWDE gene, a key player in various biological processes, including cellular signaling and development. These cell lines enable researchers to explore the functional consequences of VWDE gene loss, thereby providing invaluable insights into its role in biology and disease.

The core functionality of these knockout cell lines lies in their ability to mimic the genetic deficiencies observed in specific pathological conditions. Utilizing CRISPR-Cas9 gene editing technology, VWDE Gene Knockout Cell Lines exhibit a complete loss of VWDE expression, allowing for the study of cellular responses under conditions that replicate genetic mutations. This mechanism facilitates the precise examination of signaling pathways, gene interactions, and cellular behaviors that are crucial for understanding complex biological phenomena.

Scientifically, these cell lines have significant applications in both research and clinical contexts. They serve as indispensable tools for investigating gene function, elucidating disease mechanisms, and screening for potential therapeutic agents. The ability to model diseases associated with VWDE dysregulation makes them particularly relevant in the fields of oncology, neurology, and metabolic disorders.

Compared to alternative models, VWDE Gene Knockout Cell Lines offer several distinct advantages. Their specificity and reliability significantly enhance experimental accuracy, yielding higher reproducibility in results. Furthermore, these cell lines are optimized for various culture conditions, thus ensuring usability across different laboratory settings and protocols.

For researchers and clinicians alike, VWDE Gene Knockout Cell Lines provide an unparalleled opportunity to bridge the gap between genotype and phenotype. This product empowers users to not only investigate the fundamental biology of the VWDE gene but also to contribute to the development of novel therapeutic strategies.

Our company prides itself on being at the forefront of genetic research innovations, with a commitment to delivering high-quality biological products that advance scientific discovery and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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