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VPS37B Knockout Cell Lines

Gene: VPS37B

Official Full Name: VPS37B subunit of ESCRT-Iprovided by HGNC

Gene Summary: Enables calcium-dependent protein binding activity. Predicted to be involved in protein targeting to membrane; protein targeting to vacuole; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Located in endosome membrane; midbody; and plasma membrane. Part of ESCRT I complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12652 VPS37B Knockout cell line (HeLa) Human VPS37B 1:3~1:6 Negative Online Inquiry
KO12653 VPS37B Knockout cell line (HCT 116) Human VPS37B 1:2~1:4 Negative Online Inquiry
KO12654 VPS37B Knockout cell line (HEK293) Human VPS37B 1:3~1:6 Negative Online Inquiry
KO12655 VPS37B Knockout cell line (A549) Human VPS37B 1:3~1:4 Negative Online Inquiry

Background

VPS37B Gene Knockout Cell Lines are specifically engineered cellular models in which the VPS37B gene, integral to the endosomal sorting and cellular signaling pathways, has been completely inactivated. This product allows researchers to explore the functional implications of VPS37B depletion on various cellular processes, such as protein trafficking, cellular stress responses, and differentiation pathways. These cell lines are crafted using advanced CRISPR-Cas9 technology, ensuring precise deletion of the VPS37B gene while maintaining the integrity of the cellular environment.

These cell lines provide crucial insights into the role of VPS37B in maintaining cellular homeostasis and its potential involvement in disorders such as cancer and neurodegenerative diseases. By utilizing VPS37B Gene Knockout Cell Lines, researchers can dissect the influence of this gene on endosomal function and investigate how perturbations in this pathway can lead to pathological states. Such applications are pivotal in developing therapeutic strategies targeting VPS37B-related pathways.

One of the primary advantages of our VPS37B Gene Knockout Cell Lines is their guarantee of reproducibility and reliability compared to traditional knockdown methods, which may only partially suppress VPS37B expression. This results in more robust data supporting hypothesis-driven research. Additionally, these cell lines are validated for performance across different experimental conditions, providing a versatile tool for both academic and industrial scientists involved in basic and applied research.

With an increasing demand for high-quality cellular models, VPS37B Gene Knockout Cell Lines stand out due to their specificity, ease of use, and the potential they offer for advanced genetic studies. Our company has long been a leader in producing biologically relevant cell lines, ensuring that researchers and clinicians have access to tools that drive innovation and discovery in molecular and cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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