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VIPAS39 Knockout Cell Lines

Gene: VIPAS39

Official Full Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homologprovided by HGNC

Gene Summary: Involved in endosome to lysosome transport and intracellular protein transport. Acts upstream of or within collagen metabolic process and peptidyl-lysine hydroxylation. Located in Golgi apparatus and endosome. Part of endosome and vesicle tethering complex. Implicated in arthrogryposis, renal dysfunction, and cholestasis 2. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12682 VIPAS39 Knockout cell line (HeLa) Human VIPAS39 1:3~1:6 Negative Online Inquiry
KO12683 VIPAS39 Knockout cell line (HCT 116) Human VIPAS39 1:2~1:4 Negative Online Inquiry
KO12684 VIPAS39 Knockout cell line (HEK293) Human VIPAS39 1:3~1:6 Negative Online Inquiry
KO12685 VIPAS39 Knockout cell line (A549) Human VIPAS39 1:3~1:4 Negative Online Inquiry

Background

VIPAS39 Gene Knockout Cell Lines represent a cutting-edge tool in genetic research, specifically designed to facilitate the functional analysis of the VIPAS39 gene and its associated pathways in mammalian cells. These cell lines are engineered through precision genome editing techniques, such as CRISPR-Cas9, to create targeted deletions in the VIPAS39 gene, allowing researchers to investigate its biological role and contributions to cellular processes.

The fundamental function of these knockout cell lines is to enable the study of the loss-of-function phenotype associated with the VIPAS39 gene. This is critical for deciphering its involvement in various cellular mechanisms, including cell signaling and metabolism. By comparing the knockout cells with wild-type counterparts, researchers can observe alterations in cellular behavior, gene expression profiles, and biochemical pathways.

VIPAS39 has shown promise in various research and clinical applications, particularly in understanding conditions like cancer, metabolic disorders, and aging, where dysregulation of gene expression plays a pivotal role. The ease of use of these cell lines makes them invaluable in high-throughput screening and drug discovery processes, paving the way for identifying potential therapeutic targets.

One of the unique selling points of VIPAS39 Gene Knockout Cell Lines is their specificity and reliability. Many alternative gene knockout models offer broad or non-specific alterations, which can lead to confounding results. In contrast, VIPAS39 cell lines provide a clean knockout that ensures consistent and reproducible experimental outcomes. Furthermore, their compatibility with common laboratory protocols enhances their utility in a variety of research settings.

Researchers and clinicians will find VIPAS39 Gene Knockout Cell Lines to be a vital resource, driving forward their studies with ease and confidence in the data generated. By focusing on high-quality products and extensive validation, our company has established itself as a leader in providing advanced biological tools that cater to the nuanced needs of the scientific community, ensuring that your research endeavors are supported by the best available resources.

Please note that all services are for research use only. Not intended for any clinical use.

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