Gene: VIL1
Official Full Name: villin 1provided by HGNC
Gene Summary: This gene encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02624 | VIL1 Knockout cell line (HeLa) | Human | VIL1 | 1:3~1:6 | Negative | Online Inquiry |
KO02625 | VIL1 Knockout cell line (HCT 116) | Human | VIL1 | 1:2~1:4 | Negative | Online Inquiry |
KO02626 | VIL1 Knockout cell line (A549) | Human | VIL1 | 1:3~1:4 | Negative | Online Inquiry |
VIL1 Gene Knockout Cell Lines are engineered biological models designed to investigate the functional implications of the VIL1 gene, which encodes the protein Villin, known for its critical role in actin cytoskeleton dynamics and cellular architecture. These knockout cell lines are generated using advanced CRISPR-Cas9 technology, effectively creating a loss-of-function scenario that allows researchers to explore the biological pathways associated with Villin, including cellular motility, adhesion, and signal transduction.
The key mechanism of these cell lines involves the precise targeting and deletion of the VIL1 gene, resulting in phenotypic changes that can be analyzed in various contexts, such as cell migration assays, morphological assessments, and gene expression studies. Given the central role of Villin in cytoskeletal organization, the VIL1 gene knockout cell lines serve as invaluable tools for elucidating the contributions of this protein in normal physiology and disease states, including cancer metastasis and inflammatory responses.
Scientifically, these cell lines offer extensive applications in both research and clinical settings. They are particularly valuable in advanced cell biology studies, drug discovery, and therapeutic development, as they allow for a more profound understanding of the molecular mechanisms underlying various diseases. Compared to alternatives, VIL1 Gene Knockout Cell Lines provide researchers with knockout models that are rigorously validated, ensuring reproducibility and reliability in experimental results.
For researchers and clinicians aiming to dissect the cellular roles of the VIL1 gene, these knockout cell lines not only represent innovative solutions but also enhance experimental accuracy, enabling targeted research with potential therapeutic implications. By choosing VIL1 Gene Knockout Cell Lines, users gain access to high-quality, specialized cell models backed by our company’s commitment to excellence in genetic engineering and cellular biology research. Our expertise and dedication to advancing scientific discovery make us a leading provider of innovative biological tools tailored to meet the evolving demands of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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