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VGLL3 Knockout Cell Lines

Gene: VGLL3

Official Full Name: vestigial like family member 3provided by HGNC

Gene Summary: Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12686 VGLL3 Knockout cell line (HeLa) Human VGLL3 1:3~1:6 Negative Online Inquiry
KO12687 VGLL3 Knockout cell line (A549) Human VGLL3 1:3~1:4 Negative Online Inquiry

Background

VGLL3 Gene Knockout Cell Lines are genetically modified cell lines in which the VGLL3 gene has been selectively inactivated or "knocked out." VGLL3 is a transcriptional co-regulator implicated in various biological processes, including cell differentiation, proliferation, and interaction with multiple signaling pathways. By removing the functional VGLL3 gene, these cell lines provide a unique model for studying the gene’s specific contributions to cellular behavior, gene expression, and disease mechanisms.

The primary function of VGLL3 Gene Knockout Cell Lines lies in their ability to elucidate the biological roles of VGLL3 in various physiological and pathological contexts. Researchers can investigate how the absence of VGLL3 influences processes such as cancer cell proliferation, apoptosis, and response to therapeutic agents. The underlying mechanism involves the disruption of transcriptional regulation, leading to altered expression of target genes that may play critical roles in disease progression or regression.

Scientifically, VGLL3 knockout models are valuable for basic research and translational studies, particularly in the realms of oncology and regenerative medicine. The insights gained from these cell lines can pave the way for new therapeutic strategies targeting VGLL3-associated pathways, highlighting their importance in the identification of biomarkers and potential drug targets.

Compared to other genetic modification products, VGLL3 Gene Knockout Cell Lines stand out due to their specificity for VGLL3, providing unparalleled accuracy in delineating the gene's role within complex biological systems. The isolation of its effects allows for clearer interpretations of data and strengthens the reliability of experimental outcomes.

For researchers and clinicians, the availability of VGLL3 Gene Knockout Cell Lines represents a significant advancement in molecular biology tools, enabling detailed exploration of fundamental cellular processes and disease mechanisms in a controlled environment. With an emphasis on delivering high-quality, precisely engineered models, our company leverages extensive expertise in genetic engineering to produce these innovative cell lines, ensuring our products meet the rigorous demands of modern biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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