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VASN Knockout Cell Lines

Gene: VASN

Official Full Name: vasorinprovided by HGNC

Gene Summary: Enables transforming growth factor beta binding activity. Involved in negative regulation of epithelial to mesenchymal transition and negative regulation of transforming growth factor beta receptor signaling pathway. Located in cell surface and extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30658 VASN Knockout cell line (HeLa) Human VASN 1:3~1:6 Negative Online Inquiry
KO30659 VASN Knockout cell line (HCT 116) Human VASN 1:2~1:4 Negative Online Inquiry
KO30660 VASN Knockout cell line (HEK293) Human VASN 1:3~1:6 Negative Online Inquiry
KO30661 VASN Knockout cell line (A549) Human VASN 1:3~1:4 Negative Online Inquiry

Background

VASN Gene Knockout Cell Lines are a cutting-edge tool designed for researchers investigating the biological functions of the VASN gene in various cellular contexts. These cell lines are engineered to provide a complete knockout of the VASN gene, allowing for the study of gene-specific pathways, protein interactions, and cellular behaviors free from the influences of VASN gene expression. By utilizing CRISPR/Cas9 technology, these cell lines ensure high precision in gene editing, facilitating the generation of stable, reproducible models that accurately reflect the absence of VASN protein.

The primary mechanism of action relies on the disruption of the VASN gene, resulting in a lack of expression of its corresponding protein, which is implicated in essential processes such as cellular adhesion and signaling pathways. This makes VASN Gene Knockout Cell Lines invaluable for studying disease mechanisms, including cancer progression and metabolic disorders, where aberrations in cellular signaling are often critical.

In research and clinical settings, these cell lines allow scientists to dissect the role of the VASN gene in health and disease, providing insights that could lead to the development of targeted therapies. The high specificity and efficiency of our knockout lines reduce variables associated with off-target effects, making experiments more reliable compared to traditional knockout methods.

One distinct advantage of VASN Gene Knockout Cell Lines over alternatives lies in their comprehensive validation; each cell line undergoes rigorous testing to confirm successful gene knockout, eliminating uncertainties that commonly accompany gene editing. This ensures that researchers can focus on their experimental objectives with confidence in the results generated.

Our product is particularly valuable to molecular biologists, pharmacologists, and translational researchers who are aiming to explore the functional consequences of VASN deficiency within complex biological systems. With the increasing trend towards personalized medicine and targeted intervention strategies, having precise models at one's disposal is crucial for advancing scientific knowledge and therapy options.

At our company, we pride ourselves on our expertise in cell line development and gene editing technologies, ensuring that our VASN Gene Knockout Cell Lines exemplify the highest standards of scientific excellence and reliability in biological research. By providing robust, validated models, we empower researchers to push the boundaries of discovery in gene function and associated pathologies.

Please note that all services are for research use only. Not intended for any clinical use.

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