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VAMP8 Knockout Cell Lines

Gene: VAMP8

Official Full Name: vesicle associated membrane protein 8provided by HGNC

Gene Summary: This gene encodes an integral membrane protein that belongs to the synaptobrevin/vesicle-associated membrane protein subfamily of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). The encoded protein is involved in the fusion of synaptic vesicles with the presynaptic membrane.[provided by RefSeq, Jun 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03462 VAMP8 Knockout cell line (HeLa) Human VAMP8 1:3~1:6 Negative Online Inquiry
KO03463 VAMP8 Knockout cell line (HCT 116) Human VAMP8 1:2~1:4 Negative Online Inquiry
KO03464 VAMP8 Knockout cell line (HEK293) Human VAMP8 1:3~1:6 Negative Online Inquiry
KO03465 VAMP8 Knockout cell line (A549) Human VAMP8 1:3~1:4 Negative Online Inquiry

Background

VAMP8 Gene Knockout Cell Lines are highly specialized cell lines engineered to lack the expression of the VAMP8 gene, which encodes a vesicle-associated membrane protein critical for intracellular membrane trafficking, particularly in the context of exocytosis and endocytosis. These knockout cell lines serve as a powerful tool for researchers seeking to elucidate the biological functions of VAMP8 and its role in various cellular processes, including hormone secretion and neurotransmitter release.

The primary function of the VAMP8 gene is to mediate the fusion of vesicles with target membranes, thereby facilitating the release of biological molecules outside the cell. By creating cell lines that lack VAMP8, scientists can investigate the implications of its absence on membrane dynamics, intracellular signaling pathways, and overall cell function. This knowledge is particularly valuable in the study of diseases such as diabetes and neurodegenerative disorders, where disruptions in vesicle trafficking are often involved.

In research and clinical applications, VAMP8 Gene Knockout Cell Lines are indispensable for dissecting the molecular mechanisms underlying exocytotic processes. The unique capability to study cells devoid of VAMP8 allows for the observation of compensatory mechanisms and alternative pathways, providing deeper insights that can lead to therapeutic innovations.

Compared to traditional wild-type cell lines, VAMP8 Gene Knockout Cell Lines offer distinct advantages, including consistent and reproducible results that enhance experimental validity. These cell lines are essential for researchers looking for a reliable model system to test hypotheses relating to vesicular trafficking and its associated diseases, ultimately expediting the transition from basic research to potential clinical applications.

For scientists and clinicians, the VAMP8 Gene Knockout Cell Lines represent a crucial resource, enabling them to pursue novel research avenues with confidence and precision. Our company is dedicated to providing high-quality biological products tailored for advanced research, capitalizing on our extensive expertise in genetic engineering and cell line development to support groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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