Gene: USP32
Official Full Name: ubiquitin specific peptidase 32provided by HGNC
Gene Summary: Enables cysteine-type deubiquitinase activity. Involved in positive regulation of TORC1 signaling. Located in cytosol. Is active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06458 | USP32 Knockout cell line (HeLa) | Human | USP32 | 1:3~1:6 | Negative | Online Inquiry |
KO06459 | USP32 Knockout cell line (HCT 116) | Human | USP32 | 1:2~1:4 | Negative | Online Inquiry |
KO06460 | USP32 Knockout cell line (HEK293) | Human | USP32 | 1:3~1:6 | Negative | Online Inquiry |
KO06461 | USP32 Knockout cell line (A549) | Human | USP32 | 1:3~1:4 | Negative | Online Inquiry |
USP32 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the USP32 gene, a crucial regulator responsible for deubiquitination processes that influence protein stability and degradation in cells. These cell lines are invaluable tools for researchers investigating the role of USP32 in various biological contexts, including cellular stress responses, proliferation, and differentiation. By utilizing CRISPR/Cas9 technology, these cell lines exhibit a high specificity and efficiency in gene editing, ensuring that the relevant pathways are impacted without off-target effects, thus providing a reliable platform for functional studies.
The absence of the USP32 protein allows researchers to dissect its involvement in critical signaling pathways, offering insights into its potential links to diseases such as cancer and neurodegenerative disorders. Its role in modulating protein turnover highlights its importance in maintaining cellular homeostasis and presents opportunities for therapeutic interventions. In clinical settings, these cell lines can be pivotal for drug discovery applications, enabling high-throughput screening of compounds targeting the modified degradation pathways.
One of the main advantages of USP32 Gene Knockout Cell Lines is their reproducibility and consistency, which surpasses many traditional methods of gene silencing, such as siRNA or shRNA approaches, which may not achieve complete and stable gene modification. Moreover, these cell lines can be readily adapted for various applications, including biochemical assays, reporter gene studies, and in vivo studies when coupled with appropriate animal models.
For researchers aiming to deepen their understanding of protein regulation and its implications in health and disease, the USP32 Gene Knockout Cell Lines represent an essential resource. They enable a rigorous exploration of molecular mechanisms driving pathology while providing a strong foundation for the development of targeted therapies. Our company prides itself on delivering high-quality, cutting-edge biological products backed by years of expertise in molecular biology and genetics, ensuring that you have the best tools to advance your research.
Please note that all services are for research use only. Not intended for any clinical use.
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