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USP29 Knockout Cell Lines

Gene: USP29

Official Full Name: ubiquitin specific peptidase 29provided by HGNC

Gene Summary: Predicted to enable cysteine-type deubiquitinase activity and cysteine-type endopeptidase activity. Predicted to be involved in several processes, including G1/S transition of mitotic cell cycle; positive regulation of type I interferon-mediated signaling pathway; and protein K48-linked deubiquitination. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12745 USP29 Knockout cell line (HEK293) Human USP29 1:3~1:6 Negative Online Inquiry

Background

USP29 Gene Knockout Cell Lines are genetically-engineered cellular models specifically designed to study the functional implications of the USP29 gene, known for its role in regulating various cellular processes. By employing CRISPR/Cas9 gene editing technology, these cell lines have been created to lack the USP29 gene, enabling researchers to investigate its contributions to cellular signaling pathways, protein degradation, and the cellular stress response mechanisms.

The primary function of these knockout cell lines is to serve as a research tool for elucidating the biological roles of USP29. Through the absence of this gene, researchers can assess alterations in gene expression, protein interactions, and phenotype changes that occur as a result of USP29 deficiency. This capability is invaluable in both basic research and applied sciences, particularly in fields such as cancer biology, neurodegenerative diseases, and metabolic disorders, where the regulation of protein homeostasis is critically implicated.

The scientific importance of USP29 Gene Knockout Cell Lines lies not only in their ability to enhance understanding of gene function but also in their application as a model system for drug discovery and therapeutic interventions. With the ability to evaluate how substances affect cells deficient in USP29, researchers can identify potential pharmacological agents that may counteract the detrimental effects seen in various diseases.

One of the key advantages of utilizing USP29 Gene Knockout Cell Lines is their precision and reproducibility compared to traditional models. These cell lines are standardized and validated, providing researchers with reliable tools to generate consistent and predictable results. Furthermore, the state-of-the-art genetic engineering techniques employed to create these lines offer a higher success rate than alternative gene knockout methods, which may involve less specific means of gene disruption.

For researchers and clinicians alike, the importance of USP29 Gene Knockout Cell Lines cannot be overstated. They provide a powerful opportunity to advance knowledge about gene function and therapeutic pathways, ultimately leading to innovations in treatment strategies. With our expertise in developing advanced biological products, we are committed to empowering the scientific community with high-quality, reproducible tools that facilitate cutting-edge research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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