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UQCC6 Knockout Cell Lines

Gene: UQCC6

Official Full Name: ubiquinol-cytochrome c reductase complex assembly factor 6provided by HGNC

Gene Summary: Involved in mitochondrial cytochrome c oxidase assembly and mitochondrial respiratory chain complex III assembly. Located in mitochondrion. Is active in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12775 UQCC6 Knockout cell line (HeLa) Human UQCC6 1:3~1:6 Negative Online Inquiry
KO12776 UQCC6 Knockout cell line (HCT 116) Human UQCC6 1:2~1:4 Negative Online Inquiry
KO12777 UQCC6 Knockout cell line (HEK293) Human UQCC6 1:3~1:6 Negative Online Inquiry
KO12778 UQCC6 Knockout cell line (A549) Human UQCC6 1:3~1:4 Negative Online Inquiry

Background

UQCC6 Gene Knockout Cell Lines are a sophisticated biological research tool designed to facilitate the study of gene function and disease mechanisms by enabling targeted gene disruption in various cell types. These cell lines are generated using advanced CRISPR/Cas9 technology, which ensures precise and efficient knockout of the UQCC6 gene, a key player in mitochondrial function and cellular homeostasis. By removing the expression of UQCC6, researchers can investigate the gene's roles in metabolic processes, responses to cellular stress, and potential implications in diseases such as cancer and neurodegenerative disorders.

The primary mechanism by which UQCC6 gene knockout works involves the introduction of a double-stranded break in the target gene, prompting the cell’s repair machinery to disrupt the gene's coding sequence during the non-homologous end joining (NHEJ) repair process. Researchers utilizing these specific cell lines can uncover vital insights into how UQCC6 contributes to mitochondrial dynamics and cellular signaling pathways, making significant strides in understanding its impact on health and disease.

In the context of scientific importance, the UQCC6 Gene Knockout Cell Lines offer unprecedented applications in both basic and applied research. They serve as powerful models for drug discovery, enabling scientists to evaluate the effects of potential therapeutic agents against UQCC6-deficient cells and to explore the gene's role in drug response variability. Their utility in gene therapy preclinical studies further underscores their relevance, allowing for the examination of therapeutic interventions targeting linked metabolic pathways.

What sets our UQCC6 Gene Knockout Cell Lines apart from other gene knockout models is their high efficiency of gene disruption, confirmed by robust validation through sequencing and functional assays. This ensures that the models maintain reproducible and consistent results, critical for rigorous scientific investigations. Additionally, our cell lines are available in various relevant backgrounds, providing versatility for different experimental designs.

For researchers and clinicians alike, the value of UQCC6 Gene Knockout Cell Lines lies in their contribution to understanding the complexities of mitochondrial function and their potential to pave the way for novel therapeutic strategies. Our commitment to quality, reliability, and innovation positions our company as a leader in providing essential biological tools that cater to the needs of the scientific community. By continually refining our approaches and investing in cutting-edge technologies, we enable researchers to make groundbreaking discoveries with confidence.

Please note that all services are for research use only. Not intended for any clinical use.

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