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UNC5CL Knockout Cell Lines

Gene: UNC5CL

Official Full Name: unc-5 family C-terminal likeprovided by HGNC

Gene Summary: Enables peptidase activity. Acts upstream of or within positive regulation of JNK cascade and positive regulation of canonical NF-kappaB signal transduction. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27076 UNC5CL Knockout cell line (HEK293) Human UNC5CL 1:3~1:6 Negative Online Inquiry
KO27077 UNC5CL Knockout cell line (A549) Human UNC5CL 1:3~1:4 Negative Online Inquiry

Background

UNC5CL Gene Knockout Cell Lines represent an advanced tool in molecular biology, specifically designed for the study of gene function related to neuronal development and processing. These cell lines are engineered to have the UNC5CL gene, which plays a crucial role in regulating neuronal survival and apoptosis, inactivated. By creating a model where this gene is knocked out, researchers can precisely investigate its contributions to cellular pathways and the potential implications of UNC5CL dysregulation in neurodegenerative diseases.

The key function of these knockout cell lines lies in their ability to facilitate the elucidation of specific gene roles through comparative analysis with wild-type cells. The mechanisms of operation allow scientists to observe alterations in cellular behavior, including responses to apoptotic signals and changes in neurotrophic factor signaling. These insights are vital for understanding complex biological systems and advancing therapeutic strategies for conditions such as Alzheimer's disease and other related disorders.

From a scientific standpoint, the UNC5CL Gene Knockout Cell Lines hold significant importance in both research and clinical settings. They can serve as a robust platform for drug screening, biomarker discovery, and mechanistic studies, illuminating the pathway relationships and functional consequences of the gene's absence. Unlike traditional models, these cell lines provide a more precise representation of the biological phenomena associated with UNC5CL, improving the translational potential of findings.

The unique selling points of UNC5CL Gene Knockout Cell Lines include their high specificity and reproducibility, offering researchers reliable results that can contribute to peer-reviewed publications and grant applications. Compared to alternative gene manipulation techniques, these knockout cell lines minimize off-target effects and allow for more controlled experimental designs, ultimately leading to more valid conclusions.

For researchers and clinicians intent on advancing knowledge in neurobiology and related fields, the UNC5CL Gene Knockout Cell Lines are an invaluable resource. They not only streamline workflows but also enhance the precision of data obtained. With a commitment to excellence, our company specializes in delivering high-quality biological products and services, continually paving the way for groundbreaking discoveries in scientific research.

Please note that all services are for research use only. Not intended for any clinical use.

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