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UNC119 Knockout Cell Lines

Gene: UNC119

Official Full Name: unc-119 lipid binding chaperoneprovided by HGNC

Gene Summary: This gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33593 UNC119 Knockout cell line (HeLa) Human UNC119 1:3~1:6 Negative Online Inquiry
KO33594 UNC119 Knockout cell line (HCT 116) Human UNC119 1:2~1:4 Negative Online Inquiry
KO33595 UNC119 Knockout cell line (HEK293) Human UNC119 1:3~1:6 Negative Online Inquiry
KO33596 UNC119 Knockout cell line (A549) Human UNC119 1:3~1:4 Negative Online Inquiry

Background

UNC119 Gene Knockout Cell Lines are customized cellular models engineered to specifically disrupt the UNC119 gene, which is known to play a critical role in cellular signaling and membrane trafficking processes. These knockout cell lines provide a powerful tool for researchers to investigate the gene's function and its implications in various biological pathways and disease states.

The primary function of UNC119 Gene Knockout Cell Lines is to facilitate the study of UNC119's role in cellular mechanisms, notably its involvement in GTPase signaling pathways and the regulation of protein transport. By effectively knocking out this gene, researchers can assess changes in cellular behavior, signaling cascades, and the potential impacts on cellular homeostasis. Utilizing gene editing technologies, such as CRISPR-Cas9, these cell lines enable precise and reproducible genetic manipulation, allowing for high-throughput screening applications and functional assays.

The scientific importance of UNC119 Gene Knockout Cell Lines extends into both research and clinical settings. These cell lines are invaluable for scientists seeking to understand the etiology of diseases linked to UNC119 dysregulation, such as certain neurological disorders and cancers. The insights gained from experiments using these models can lead to the development of targeted therapies and novel interventions, making them crucial in translational research.

One of the standout advantages of UNC119 Gene Knockout Cell Lines is their specificity and reliability compared to traditional methods, such as chemical inhibitors or siRNA knockdown, which may produce off-target effects or incomplete knockdown. Moreover, our state-of-the-art cell lines come with detailed characterization data, ensuring experimental reproducibility and robustness. This unique offering empowers researchers to pursue their studies with confidence, knowing they are utilizing a high-quality, validated model.

In a rapidly evolving scientific landscape, the value of UNC119 Gene Knockout Cell Lines cannot be overstated. They provide an essential resource for elucidating complex biological processes, fostering innovation in drug discovery, and laying the groundwork for cutting-edge therapies. Our company specializes in the development of high-quality biological research tools, drawing on extensive expertise in genetic engineering and cell line development, ensuring that our customers have access to the best resources for their scientific inquiries.

Please note that all services are for research use only. Not intended for any clinical use.

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