Gene: ULK4
Official Full Name: unc-51 like kinase 4provided by HGNC
Gene Summary: This gene encodes a member of the unc-51-like serine/threonine kinase (STK) family. Members of this protein family play a role in neuronal growth and endocytosis. The encoded protein is likely involved in neurite branching, neurite elongation and neuronal migration. Genome-wide association studies (GWAS) indicate an association of variations in this gene with blood pressure and hypertension. Sequence variations in this gene may also be be associated with psychiatric disorders, including schizophrenia and bipolar disorder. Pseudogenes associated with this gene have been identified and are located on chromosome 15. [provided by RefSeq, Jul 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12810 | ULK4 Knockout cell line (HeLa) | Human | ULK4 | 1:3~1:6 | Negative | Online Inquiry |
KO12811 | ULK4 Knockout cell line (HCT 116) | Human | ULK4 | 1:2~1:4 | Negative | Online Inquiry |
KO12812 | ULK4 Knockout cell line (HEK293) | Human | ULK4 | 1:3~1:6 | Negative | Online Inquiry |
KO12813 | ULK4 Knockout cell line (A549) | Human | ULK4 | 1:3~1:4 | Negative | Online Inquiry |
ULK4 Gene Knockout Cell Lines are meticulously engineered cellular models designed to investigate the role of the ULK4 gene in various biological processes. Utilizing the CRISPR-Cas9 genome editing technology, these cell lines have been developed to specifically disrupt ULK4 gene expression, facilitating detailed studies into its function and implications in cellular pathways related to autophagy, neurogenesis, and cancer biology.
The primary function of these ULK4 knockout cell lines is to provide researchers with a platform to explore the mechanistic underpinnings of ULK4 in cell signaling and homeostasis. By eliminating ULK4 expression, researchers can observe the resultant phenotypic changes, providing insights into its regulatory roles in cellular metabolism and survival. This is crucial for understanding diseases where ULK4 has been implicated, including various neurodegenerative disorders and malignancies.
In terms of scientific importance, the ULK4 Gene Knockout Cell Lines serve as invaluable tools in both fundamental research and potential clinical applications. They enable the exploration of therapeutic targets and the development of novel treatment strategies by elucidating ULK4's contribution to autophagy regulation and its interactions in complex biochemical networks.
Compared to alternative models, which may lack specificity or fidelity in gene expression, these knockout lines provide a precise and robust approach to study ULK4. Their design ensures reproducibility and enhances the reliability of findings, making them superior for applications requiring high experimental rigor.
For researchers and clinicians seeking to deepen their understanding of gene function in disease contexts, the ULK4 Gene Knockout Cell Lines offer an unparalleled resource. By applying these cell lines, users can significantly advance their research endeavors, leading to new discoveries in genomic regulation and therapeutic innovation.
Our company prides itself on expertise in molecular biology and cell line development, ensuring that our products meet the highest standards of quality and reliability for cutting-edge research applications. With a commitment to advancing scientific knowledge, we are dedicated to supporting the needs of the global research community.
Please note that all services are for research use only. Not intended for any clinical use.
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