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UFC1 Knockout Cell Lines

Gene: UFC1

Official Full Name: ubiquitin-fold modifier conjugating enzyme 1provided by HGNC

Gene Summary: UFC1 is an E2-like conjugating enzyme for ubiquitin-fold modifier-1 (UFM1; MIM 610553) (Komatsu et al., 2004 [PubMed 15071506]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22463 UFC1 Knockout cell line (HeLa) Human UFC1 1:3~1:6 Negative Online Inquiry
KO22464 UFC1 Knockout cell line (HCT 116) Human UFC1 1:2~1:4 Negative Online Inquiry
KO22465 UFC1 Knockout cell line (HEK293) Human UFC1 1:3~1:6 Negative Online Inquiry
KO22466 UFC1 Knockout cell line (A549) Human UFC1 1:3~1:4 Negative Online Inquiry

Background

UFC1 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to eliminate the expression of the UFC1 gene, a critical regulator in cellular processes such as ubiquitination. This product facilitates the study of the functional implications of UFC1 loss in various biological contexts. By utilizing CRISPR/Cas9 gene-editing technology, these cell lines provide researchers with powerful tools to investigate the pathways affected by UFC1, thus unveiling its role in cellular signaling and protein homeostasis.

The key function of the UFC1 Gene Knockout Cell Lines lies in their ability to generate precise, stable knockouts that allow for the analysis of UFC1’s contribution to Ub-mediated signaling cascades. The absence of UFC1 helps to delineate its functions in proteosomal degradation, stress responses, and overall cellular metabolic regulation. Such insights are invaluable in understanding diseases linked to misregulation of ubiquitination, including cancers and neurodegenerative disorders.

In research and clinical settings, these cell lines are indispensable for elucidating mechanisms of drug resistance, identifying potential therapeutic targets, and enabling high-throughput screening processes. Their usage in functional assays greatly enhances the ability to discover and develop novel interventions that could modulate UFC1’s activity.

What sets our UFC1 Gene Knockout Cell Lines apart from alternatives is the rigor of our genetic validation processes, ensuring high specificity and reproducibility. These cell lines are developed using our proprietary methods, which provide enhanced reliability in results, a critical factor in quality research and drug development. Furthermore, they are available in multiple relevant background strains, catering to diverse experimental needs.

For researchers and clinicians focused on advancing their understanding of ubiquitin-related mechanisms, UFC1 Gene Knockout Cell Lines offer an unmatched solution. Our commitment to quality and innovation is underscored by our team of experienced professionals in molecular biology, ensuring that the products we deliver are at the forefront of scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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