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UBE2Z Knockout Cell Lines

Gene: UBE2Z

Official Full Name: ubiquitin conjugating enzyme E2 Zprovided by HGNC

Gene Summary: This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis. [provided by RefSeq, Feb 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12850 UBE2Z Knockout cell line (HeLa) Human UBE2Z 1:3~1:6 Negative Online Inquiry
KO12851 UBE2Z Knockout cell line (HCT 116) Human UBE2Z 1:2~1:4 Negative Online Inquiry
KO12852 UBE2Z Knockout cell line (HEK293) Human UBE2Z 1:3~1:6 Negative Online Inquiry
KO12853 UBE2Z Knockout cell line (A549) Human UBE2Z 1:3~1:4 Negative Online Inquiry

Background

UBE2Z Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the UBE2Z gene, which encodes a ubiquitin-conjugating enzyme involved in protein degradation and cellular regulation processes. These cell lines are pivotal tools for researchers aiming to investigate the specific roles of UBE2Z in various biological contexts, particularly in cancer biology, neurodegenerative diseases, and cellular stress responses. By employing CRISPR/Cas9 gene-editing technology, UBE2Z Gene Knockout Cell Lines provide a reliable means to dissect the functional consequences of UBE2Z deficiency, enabling insights into its influence on protein homeostasis and signal transduction pathways.

The key functionality of these knockout cell lines lies in their ability to delineate the molecular mechanisms by which UBE2Z modulates cellular fate. UBE2Z is known to be involved in the ubiquitination of key substrates that regulate cell cycle progression and apoptosis, making these cell lines especially valuable for elucidating pathways that may be therapeutic targets. In clinical and research settings, the UBE2Z knockout models allow for robust experimentation that can lead to the identification of biomarkers or the development of novel therapeutic strategies.

One significant advantage of using UBE2Z Gene Knockout Cell Lines is their specificity; unlike traditional pharmacological inhibitors that may affect multiple pathways, these knockout lines provide a clean genetic background to study the effects of UBE2Z loss without off-target consequences. Additionally, they offer reproducibility and consistency in experiments, which are crucial for rigorous scientific inquiry.

For researchers and clinicians venturing into protein degradation pathways or those exploring novel therapeutic approaches in oncology or neurology, these cell lines serve as indispensable tools that can facilitate groundbreaking discoveries. Our company has a dedicated track record of delivering high-quality biological products, and UBE2Z Gene Knockout Cell Lines exemplify our commitment to empowering the scientific community with precise and effective research tools.

Please note that all services are for research use only. Not intended for any clinical use.

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