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UBE2F Knockout Cell Lines

Gene: UBE2F

Official Full Name: ubiquitin conjugating enzyme E2 F (putative)provided by HGNC

Gene Summary: Enables NEDD8 conjugating enzyme activity. Involved in protein neddylation. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01679 UBE2F Knockout cell line (HeLa) Human UBE2F 1:3~1:6 Negative Online Inquiry
KO01680 UBE2F Knockout cell line (HCT 116) Human UBE2F 1:2~1:4 Negative Online Inquiry
KO01681 UBE2F Knockout cell line (HEK293) Human UBE2F 1:3~1:6 Negative Online Inquiry
KO01682 UBE2F Knockout cell line (A549) Human UBE2F 1:3~1:4 Negative Online Inquiry

Background

UBE2F Gene Knockout Cell Lines are genetically modified cellular models designed to facilitate the study of the UBE2F gene's functional role and its implications in various biological processes. UBE2F encodes an E2 ubiquitin-conjugating enzyme, integral to the ubiquitin-proteasome system, which plays a crucial role in protein degradation, cell cycle regulation, and response to cellular stress. By employing CRISPR/Cas9 or other gene-editing technologies, these knockout cell lines have been precisely engineered to lack functional UBE2F, enabling researchers to observe phenotypic manifestations and molecular pathways directly influenced by UBE2F absence.

The primary function of these cell lines is to provide a controlled environment for dissecting the contributions of UBE2F in oncogenic processes, cellular differentiation, and responses to therapeutic agents. The lack of UBE2F allows researchers to elucidate its role in regulatory networks involving protein stability and enzyme activity, thus offering valuable insights into its potential as a therapeutic target.

In scientific research, UBE2F Gene Knockout Cell Lines serve as critical tools in understanding the molecular underpinnings of diseases such as cancer and neurodegeneration, thereby paving the way for novel therapeutic strategies. They are particularly relevant in the fields of pharmacology and biotechnology, where precise gene modulation can inform drug development and efficacy testing.

Compared to alternative products, our UBE2F Gene Knockout Cell Lines offer unparalleled specificity and reliability, with comprehensive validation steps ensuring that genotype alterations correlate with expected phenotypic changes. Researchers gain enhanced reproducibility in experimental results due to the standardized protocols used during generation, ensuring consistency across studies.

For researchers and clinicians, investing in UBE2F Gene Knockout Cell Lines significantly accelerates the discovery of UBE2F-related pathways and downstream effects, ultimately contributing to innovative biomedical advancements. Our company, dedicated to providing high-quality biological products, combines extensive expertise in gene editing with a commitment to supporting the scientific community, ensuring that our offerings remain at the forefront of research innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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