Home / Tmem65 Knockout Cell Lines

Tmem65 Knockout Cell Lines

Gene: Tmem65

Official Full Name: transmembrane protein 65provided by MGI

Gene Summary: Involved in cardiac conduction; cardiac ventricle development; and regulation of cardiac conduction. Located in intercalated disc and plasma membrane. Is expressed in dentate gyrus subgranular zone. Orthologous to human TMEM65 (transmembrane protein 65). [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01062 Tmem65 Knockout cell line (NIH/3T3) Mouse Tmem65 1:3~1:5 Negative Online Inquiry

Background

Tmem65 Gene Knockout Cell Lines are genetically engineered cell lines in which the Tmem65 gene has been inactivated, providing a vital tool for studying the role of this gene in various biological processes. Tmem65, known to play a critical role in mitochondrial function and cellular metabolism, is implicated in neurodegenerative diseases and other cellular dysfunctions. By employing CRISPR/Cas9 gene-editing technology, these cell lines facilitate the precise knockout of the Tmem65 gene, enabling researchers to investigate the phenotypic consequences of this genetic alteration.

The primary function of these knockout cell lines is to elucidate the molecular pathways influenced by Tmem65. The absence of this gene allows scientists to observe changes in mitochondrial dynamics, energy production, and metabolic profiling, thereby revealing insights into pathology related to mitochondrial dysfunction. Furthermore, the cell lines serve as a model for understanding the genetic underpinnings of diseases such as Alzheimer’s and other age-related disorders, making them invaluable for both academic research and clinical applications.

One of the distinctive advantages of Tmem65 Gene Knockout Cell Lines is their potential to yield reproducible and relevant data, which can inform drug development and therapeutic strategies. Compared to traditional models, such as whole-organism studies or less-specific genetic manipulation methods, these cell lines provide a controlled environment, reducing variability and enhancing the reliability of experimental outcomes. Moreover, they provide a highly accessible platform for high-throughput screening and functional assays.

For researchers and clinicians focused on mitochondrial biology, neurobiology, or genetic diseases, these knockout cell lines represent a powerful resource that enhances the understanding of complex molecular mechanisms. By contributing significantly to the research landscape, Tmem65 Gene Knockout Cell Lines aid in bridging the gap between basic research and therapeutic advancements, making them essential tools for pioneering innovations in health and disease management.

As a leading company in biotechnology, we leverage state-of-the-art techniques and expertise to provide researchers with high-quality biological products designed to advance scientific discovery. Our commitment to excellence ensures that our cell lines are validated, thoroughly characterized, and optimized for diverse research needs.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.