Gene: TWSG1
Official Full Name: twisted gastrulation BMP signaling modulator 1provided by HGNC
Gene Summary: Enables transforming growth factor beta binding activity. Involved in negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of cytokine production; and positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20254 | TWSG1 Knockout cell line (HeLa) | Human | TWSG1 | 1:3~1:6 | Negative | Online Inquiry |
KO20255 | TWSG1 Knockout cell line (HCT 116) | Human | TWSG1 | 1:2~1:4 | Negative | Online Inquiry |
KO20256 | TWSG1 Knockout cell line (HEK293) | Human | TWSG1 | 1:3~1:6 | Negative | Online Inquiry |
KO20257 | TWSG1 Knockout cell line (A549) | Human | TWSG1 | 1:3~1:4 | Negative | Online Inquiry |
TWSG1 Gene Knockout Cell Lines are specially engineered cellular systems designed to lack the TWSG1 gene, which encodes the protein Twisted Gastrulation. This gene is pivotal in regulating various biological processes, including embryonic development and cell signaling pathways involved in the growth and differentiation of several cell types. By creating knockout models, researchers can investigate the precise functions and mechanisms of TWSG1 in various biological contexts.
The key function of TWSG1 Gene Knockout Cell Lines lies in their ability to serve as a controlled environment for studying the implications of TWSG1 deficiency. The absence of the TWSG1 protein allows for the examination of altered cellular behaviors, enabling scientists to elucidate its role in developmental biology and disease states. Utilizing loss-of-function models promotes a deeper understanding of signaling interactions and gene regulatory networks.
In a research or clinical setting, these knockout cell lines hold considerable scientific importance as they help advance our knowledge of diseases influenced by aberrant TWSG1 function, including certain cancers and developmental disorders. Furthermore, they provide a critical platform for drug screening and therapeutic development, allowing for the identification of potential pharmacological interventions.
What sets TWSG1 Gene Knockout Cell Lines apart from alternative models is their rigorously validated genetic modifications and optimized growth conditions, ensuring reproducibility and reliability in experimental outcomes. Researchers and clinicians value these cell lines for their versatility and the detailed insights they can provide into complex biological questions.
In conclusion, TWSG1 Gene Knockout Cell Lines offer researchers a powerful tool for dissecting gene function and elucidating pathways relevant to human health and disease. Our company prides itself on extensive expertise in genetic engineering and cell line development, delivering high-quality biological products designed to empower scientific discovery and innovation in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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