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TWF2 Knockout Cell Lines

Gene: TWF2

Official Full Name: twinfilin actin binding protein 2provided by HGNC

Gene Summary: The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved actin monomer-binding protein. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03818 TWF2 Knockout cell line (HeLa) Human TWF2 1:3~1:6 Negative Online Inquiry
KO03819 TWF2 Knockout cell line (HCT 116) Human TWF2 1:2~1:4 Negative Online Inquiry
KO03820 TWF2 Knockout cell line (HEK293) Human TWF2 1:3~1:6 Negative Online Inquiry
KO03821 TWF2 Knockout cell line (A549) Human TWF2 1:3~1:4 Negative Online Inquiry

Background

TWF2 Gene Knockout Cell Lines are genetically engineered cell lines where the TWF2 gene has been selectively disrupted, enabling researchers to study the functions and effects of TWF2 with high specificity. This product is designed to facilitate fundamental research in molecular biology, particularly in the context of cellular signaling, motility, and various pathophysiological conditions, including cancer metastasis and neurodegenerative diseases.

The primary function of TWF2, a member of the twinfilin family, is to regulate actin dynamics within the cell. By providing a knockout model, these cell lines allow researchers to investigate how the absence of TWF2 influences actin filament organization, cellular morphology, and migration pathways. The mechanism of action involves assessing alterations in cytoskeletal dynamics and cellular responses to extracellular stimuli, thereby shedding light on the gene’s role in critical biological processes.

The scientific importance of these knockout cell lines is underscored by their applications in experimental research and clinical studies. They serve as indispensable tools for understanding the underlying mechanisms of diseases linked to TWF2 dysregulation and for evaluating potential therapeutic strategies. Researchers can utilize these models to screen for drug candidates, assess the efficacy of existing treatments, and unravel the complexities of cellular interactions in health and disease.

TWF2 Gene Knockout Cell Lines stand out due to their precise genetic modification, allowing for a more reliable interpretation of experimental outcomes compared to alternative models, such as wild-type cell lines or other genetic knockouts. Furthermore, they enable reproducible and scalable studies with a lower likelihood of confounding variables, ultimately supporting more robust data collection.

Given the increasing demand for accurate modeling in biological research, these knockout cell lines are of paramount value to researchers and clinicians alike. They provide a pathway for innovative discoveries and applications, advancing the understanding of critical cellular functions and disease mechanisms. As a company renowned for our expertise in genetic engineering and cell line development, we offer high-quality products designed to meet the rigorous demands of the scientific community, ensuring that our customers have the best tools at their disposal for cutting-edge research.

Please note that all services are for research use only. Not intended for any clinical use.

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