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TUT7 Knockout Cell Lines

Gene: TUT7

Official Full Name: terminal uridylyl transferase 7provided by HGNC

Gene Summary: Enables RNA uridylyltransferase activity and miRNA binding activity. Involved in RNA metabolic process and transposable element silencing by mRNA destabilization. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12922 TUT7 Knockout cell line (HeLa) Human TUT7 1:3~1:6 Negative Online Inquiry
KO12923 TUT7 Knockout cell line (HCT 116) Human TUT7 1:2~1:4 Negative Online Inquiry
KO12924 TUT7 Knockout cell line (HEK293) Human TUT7 1:3~1:6 Negative Online Inquiry
KO12925 TUT7 Knockout cell line (A549) Human TUT7 1:3~1:4 Negative Online Inquiry

Background

TUT7 Gene Knockout Cell Lines represent a pioneering advancement in functional genomics and cell biology, specifically designed to elucidate the role of the TUT7 gene in various biological processes. These cell lines are produced through targeted CRISPR-Cas9 gene editing technology, ensuring a precise knockout of the TUT7 gene. This technique offers unparalleled specificity and efficiency, enabling researchers to observe the resultant phenotypic changes and understand the gene's contributions to cellular functions, such as RNA regulation and post-transcriptional modification.

The key mechanisms underlying the TUT7 Gene Knockout involve disrupted pathways related to RNA polyadenylation and decay, subsequently affecting gene expression and stability. By utilizing these knockout cell lines, researchers can delve into the downstream effects of TUT7 functional loss, thereby providing insights into its implications in various diseases, including cancers and neurodegenerative disorders.

The scientific importance of TUT7 Gene Knockout Cell Lines extends to both research and clinical applications. In research settings, they serve as valuable tools for drug discovery, validating therapeutic targets and mechanisms of action. Clinically, understanding TUT7's role can lead to biomarker identification and the development of novel therapeutic interventions.

Compared to alternative models, such as transient transfection systems or conventional knockout methods, these cell lines provide a stable, reproducible platform for long-term studies. Their adaptability enables use across multiple experimental conditions, facilitating comprehensive analysis and yielding consistent results.

For researchers and clinicians focused on the intricate workings of gene function and pathogenesis, TUT7 Gene Knockout Cell Lines offer a robust solution that expedites discoveries and fosters innovation. Our company prides itself on delivering high-quality biological products, backed by extensive experience in gene editing technologies and a commitment to advancing scientific research.

Please note that all services are for research use only. Not intended for any clinical use.

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