Gene: TUBAL3
Official Full Name: tubulin alpha like 3provided by HGNC
Gene Summary: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in microtubule cytoskeleton. Predicted to be active in cytoplasm and microtubule. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12936 | TUBAL3 Knockout cell line (A549) | Human | TUBAL3 | 1:3~1:4 | Negative | Online Inquiry |
TUBAL3 Gene Knockout Cell Lines are specialized experimental tools designed to facilitate the study of the TUBAL3 gene's function by eliminating its expression in cellular models. These cell lines are engineered using cutting-edge CRISPR-Cas9 technology, which allows for precise and efficient genome editing. By creating knockout models, researchers can investigate the specific roles of the TUBAL3 gene in various biological processes, including cell proliferation, differentiation, and response to external stimuli.
The primary mechanism by which TUBAL3 gene knockout cell lines operate is through the introduction of targeted double-strand breaks in the DNA sequence associated with the TUBAL3 gene. This disruption leads to frameshift mutations that prevent the production of functional TUBAL3 protein. Consequently, the resulting phenotypic variations can be systematically analyzed to glean insights into the gene's functions and its pathways.
The scientific importance of these cell lines cannot be overstated, as they serve as invaluable models in both research and clinical settings. They enable further understanding of disease mechanisms, particularly in cancer biology where TUBAL3-related pathways may be implicated. Additionally, these cell lines provide a platform for drug discovery and testing, as they allow researchers to evaluate therapeutic interventions' efficacy in gene-specific contexts.
Compared to traditional gene silencing approaches, such as RNA interference (RNAi), TUBAL3 gene knockout cell lines offer unique advantages, including permanent gene disruption and the ability to generate stable cell line populations. This permanence significantly enhances the reliability of experimental outcomes, enabling long-term studies that are vital in discerning complex genetic interactions.
For researchers and clinicians dedicated to understanding gene function and its implications in health and disease, TUBAL3 Gene Knockout Cell Lines represent an essential resource. By employing these cell lines, you can accelerate your discoveries and enhance the rigor of your research.
Our company has extensive expertise in the development of advanced genetic tools and models. We are committed to providing high-quality biological products that empower the scientific community to push the boundaries of discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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