Home / TUBA4B Knockout Cell Lines

TUBA4B Knockout Cell Lines

Gene: TUBA4B

Official Full Name: tubulin alpha 4bprovided by HGNC

Gene Summary: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in microtubule cytoskeleton. Predicted to be active in cytoplasm and microtubule. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26241 TUBA4B Knockout cell line (A549) Human TUBA4B 1:3~1:4 Negative Online Inquiry

Background

TUBA4B Gene Knockout Cell Lines are a cutting-edge biological tool designed to aid researchers in uncovering the physiological roles of the TUBA4B gene, which encodes the Tubulin Alpha-4B chain, an integral component of microtubule structure. By utilizing CRISPR/Cas9 gene-editing technology, these knockout cell lines facilitate the precise and permanent inactivation of the TUBA4B gene, allowing for an in-depth analysis of its function in processes such as cell division, intracellular transport, and cytoskeletal organization.

The key function of the TUBA4B Gene Knockout Cell Lines lies in their capacity to serve as experimental models for understanding the implications of diminished TUBA4B expression. By observing phenotypic and molecular changes in these cells, researchers can elucidate the gene's involvement in neurodegenerative disorders and other pathological conditions where microtubule stability is compromised. This mechanistic insight is crucial for developing targeted therapies and advancing our understanding of cellular dynamics.

In clinical settings and research, the TUBA4B Gene Knockout Cell Lines offer an innovative approach to studying microtubule-associated diseases, proving invaluable for both academic and pharmaceutical laboratories. Their unique ability to mimic disease-associated states enhances translational research potential, providing a platform for drug discovery and therapeutic testing.

Compared to existing alternatives, these cell lines promise greater specificity and reliability due to their precise modification capabilities. Many traditional knockdown methods, such as RNA interference, can lead to off-target effects or incomplete gene silencing, while the CRISPR/Cas9 technology employed in TUBA4B knockout lines effectively eliminates the gene of interest, yielding clear and reproducible results.

This product is not just a research tool; it is a pivotal asset for any laboratory seeking to advance their understanding of microtubule functions and associated diseases. For researchers and clinicians eager to explore the complexities of TUBA4B in cellular pathways, our gene knockout cell lines stand out for their efficiency and precision, greatly enhancing experimental outcomes.

Our company prides itself on a commitment to excellence in cellular and molecular biology research tools, backed by extensive expertise in genetic engineering. With our TUBA4B Gene Knockout Cell Lines, you are not merely obtaining a product; you are leveraging state-of-the-art technology that supports groundbreaking research and contributes to the advancement of medical science.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.