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TTC9 Knockout Cell Lines

Gene: TTC9

Official Full Name: tetratricopeptide repeat domain 9provided by HGNC

Gene Summary: This gene encodes a protein that contains three tetratricopeptide repeats. The gene has been shown to be hormonally regulated in breast cancer cells and may play a role in cancer cell invasion and metastasis. [provided by RefSeq, Mar 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29223 TTC9 Knockout cell line (HeLa) Human TTC9 1:3~1:6 Negative Online Inquiry
KO29224 TTC9 Knockout cell line (HCT 116) Human TTC9 1:2~1:4 Negative Online Inquiry
KO29225 TTC9 Knockout cell line (HEK293) Human TTC9 1:3~1:6 Negative Online Inquiry
KO29226 TTC9 Knockout cell line (A549) Human TTC9 1:3~1:4 Negative Online Inquiry

Background

TTC9 Gene Knockout Cell Lines are specifically engineered cellular models that have undergone targeted gene disruption of the TTC9 gene, which is integral to various cellular processes including protein interactions and regulatory pathways. These knockout cell lines serve as invaluable tools for researchers investigating the biological implications of TTC9 loss and its potential role in pathologies such as cancer and neurodegenerative diseases.

The primary function of the TTC9 Gene Knockout Cell Lines lies in their ability to provide a controlled environment to explore the consequences of gene loss. These cell lines utilize CRISPR-Cas9 technology for gene editing, allowing for precise genome modification. The depletion of TTC9 leads to altered signaling cascades and cellular responses that can be quantitatively assessed, thereby elucidating its role in cell proliferation, differentiation, and apoptosis.

Scientifically, these knockout models are crucial in understanding the molecular mechanisms underlying diseases, as they allow for direct correlation between gene function and phenotypic outcomes. The implications extend to drug discovery and development, where researchers can screen novel therapeutic compounds that may target the pathways influenced by TTC9.

Compared to traditional cell lines, which may express varying levels of the target gene, TTC9 Gene Knockout Cell Lines provide a consistent and reproducible model. This eliminates confounding variables and enhances the reliability of experimental results. Moreover, the accessibility of these knockout lines facilitates high-throughput screening and large-scale experiments, which are essential in today's fast-paced research environment.

For researchers and clinicians alike, the value of TTC9 Gene Knockout Cell Lines is profound; they not only enable the dissection of complex genetic interactions but also aid in the development of targeted gene therapies. By offering tailored solutions that expedite research timelines and improve the accuracy of findings, we position ourselves as leaders in the field of advanced biological products. Our team is committed to supporting scientific discovery with unparalleled expertise and high-quality research tools, ensuring that our customers achieve groundbreaking results in their pursuits.

Please note that all services are for research use only. Not intended for any clinical use.

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