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TSPAN33 Knockout Cell Lines

Gene: TSPAN33

Official Full Name: tetraspanin 33provided by HGNC

Gene Summary: Enables enzyme binding activity. Involved in pore complex assembly; protein localization to plasma membrane; and protein maturation. Located in plasma membrane. Part of pore complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12987 TSPAN33 Knockout cell line (HeLa) Human TSPAN33 1:3~1:6 Negative Online Inquiry
KO12988 TSPAN33 Knockout cell line (HCT 116) Human TSPAN33 1:2~1:4 Negative Online Inquiry
KO12989 TSPAN33 Knockout cell line (HEK293) Human TSPAN33 1:3~1:6 Negative Online Inquiry
KO12990 TSPAN33 Knockout cell line (A549) Human TSPAN33 1:3~1:4 Negative Online Inquiry

Background

TSPAN33 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology and genetics research. These cell lines have been engineered to lack the TSPAN33 gene, facilitating the study of its function and implications in various biological processes. TSPAN33, a member of the tetraspanin family, is implicated in cellular signaling, immune response, and cancer progression, making these knockout cell lines invaluable for researchers focusing on these areas.

The primary mechanism by which TSPAN33 knockout cell lines operate involves the disruption of TSPAN33-related signaling pathways. The absence of this gene allows scientists to investigate downstream effects, such as changes in cellular adhesion, proliferation, and immune response modulation. By assessing how the loss of TSPAN33 alters cellular behavior, researchers can better understand its role in health and disease, which is pivotal in the development of targeted therapies, particularly in oncology and immunology.

From a scientific perspective, these knockout cell lines are of immense importance as they provide a controlled environment for exploration of gene function and interaction within the context of various signaling cascades. Applications range from basic cell biology studies to more applied clinical research, offering insights that could pave the way for novel therapeutic strategies.

The specific advantages of TSPAN33 Gene Knockout Cell Lines lie in their precise genetic modification, ensuring reproducibility and reliability in experimental results. Compared to traditional methods, such as RNA interference or pharmacological inhibitors, knockout cell lines offer a more definitive approach by providing complete gene ablation, which helps eliminate off-target effects and variables during research.

In conclusion, TSPAN33 Gene Knockout Cell Lines serve as a powerful resource for researchers and clinicians aiming to delve deeper into the molecular mechanisms of diseases. Their ability to elucidate the role of TSPAN33 enhances our understanding of critical biological processes. Our company specializes in the development of high-quality, genetically modified cell lines, backed by years of expertise and a commitment to advancing scientific research, enabling our customers to expedite their studies and improve outcomes in their experimental endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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