Gene: TSPAN14
Official Full Name: tetraspanin 14provided by HGNC
Gene Summary: Enables enzyme binding activity. Involved in positive regulation of Notch signaling pathway; protein localization to plasma membrane; and protein maturation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25690 | TSPAN14 Knockout cell line (HeLa) | Human | TSPAN14 | 1:3~1:6 | Negative | Online Inquiry |
KO25691 | TSPAN14 Knockout cell line (HCT 116) | Human | TSPAN14 | 1:2~1:4 | Negative | Online Inquiry |
KO25692 | TSPAN14 Knockout cell line (HEK293) | Human | TSPAN14 | 1:3~1:6 | Negative | Online Inquiry |
KO25693 | TSPAN14 Knockout cell line (A549) | Human | TSPAN14 | 1:3~1:4 | Negative | Online Inquiry |
TSPAN14 Gene Knockout Cell Lines are genetically engineered cell cultures that lack the expression of the TSPAN14 gene, a member of the tetraspanin family known to play critical roles in cellular functions such as adhesion, migration, and signaling. These knockout cell lines serve as invaluable tools for elucidating the biological functions of TSPAN14 and its implications in various physiological and pathological processes.
The primary function of TSPAN14 involves modulating cell surface protein interactions and influencing cellular signaling pathways, which has been associated with immune responses and cancer progression. By utilizing TSPAN14 Gene Knockout Cell Lines, researchers can observe the resulting phenotypic changes, enabling them to dissect the precise mechanisms by which TSPAN14 contributes to cell behavior, including its role in immune cell activation and tumor microenvironment interactions.
Scientifically, these knockout cell lines are critical for advancing research in areas such as immunology, oncology, and developmental biology. They provide a controlled platform for testing hypotheses regarding TSPAN14's involvement in diseases, enhancing drug discovery processes, and facilitating the development of targeted therapies. Their relevance extends into clinical research, where understanding host-pathogen interactions and immune evasion strategies may lead to breakthroughs in treatment strategies.
One of the key advantages of our TSPAN14 Gene Knockout Cell Lines is their high specificity and reproducibility, allowing for consistent results across experiments, which is a significant improvement over alternative approaches such as RNA interference that may produce off-target effects. Furthermore, our cell lines are derived from established parental cell lines, ensuring robustness and reliability in experimental applications.
The value of TSPAN14 Gene Knockout Cell Lines for researchers and clinicians lies in their ability to provide critical insights that could lead to innovative therapeutic strategies. With a focus on quality and precision, our product enables users to push the boundaries of current knowledge and discover novel pathways involved in human health and disease.
Our company's expertise in genetic engineering and cell line development ensures that we offer top-tier biological products tailored to meet the evolving needs of the research community. We are committed to advancing scientific discovery and providing the tools necessary for groundbreaking research and clinical application.
Please note that all services are for research use only. Not intended for any clinical use.
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