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TSPAN1 Knockout Cell Lines

Gene: TSPAN1

Official Full Name: tetraspanin 1provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32285 TSPAN1 Knockout cell line (HeLa) Human TSPAN1 1:3~1:6 Negative Online Inquiry
KO32286 TSPAN1 Knockout cell line (HCT 116) Human TSPAN1 1:2~1:4 Negative Online Inquiry
KO32287 TSPAN1 Knockout cell line (A549) Human TSPAN1 1:3~1:4 Negative Online Inquiry

Background

TSPAN1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the TSPAN1 gene, a member of the tetraspanin family known to play critical roles in various cellular processes, including cell adhesion, signaling, and immune response modulation. The creation of these knockout lines is accomplished through advanced CRISPR-Cas9 gene-editing technology, ensuring precise and efficient disruption of the TSPAN1 gene.

The primary function of TSPAN1 involves facilitating interactions between different membrane proteins, thereby influencing cell behavior and signaling pathways. By knocking out the TSPAN1 gene, researchers can study its impact on cell proliferation, migration, differentiation, and response to therapeutic agents. This allows for a deeper understanding of how TSPAN1 contributes to disease mechanisms, particularly in cancer biology and immune responses.

The scientific importance of TSPAN1 Gene Knockout Cell Lines is profound, serving as valuable tools in both basic research and clinical settings. They can help elucidate the role of TSPAN1 in tumorigenesis, offering potential insights into novel cancer treatment strategies. Furthermore, these knockout lines can be utilized in drug discovery, toxicity testing, and in investigating the efficacy of immunotherapies, making them indispensable for advancing personalized medicine.

Compared to alternative models, TSPAN1 Gene Knockout Cell Lines provide researchers with a unique advantage of specificity and reproducibility. Unlike naturally occurring cell lines where genetic variability may obscure results, these knockout cells ensure consistent genetic backgrounds, leading to more reliable data and insights.

For researchers, clinicians, and pharmaceutical companies, the adoption of TSPAN1 Gene Knockout Cell Lines offers a compelling opportunity to accelerate discoveries that may inform future therapies. By enabling the detailed study of TSPAN1's role in health and disease, these cell lines hold the potential to bridge gaps in our understanding and drive innovation in therapeutic strategies.

Our company specializes in high-quality biological products and genetic models, backed by rigorous research and development. With a focus on precision and reliability, we are committed to supporting the scientific community in its quest for transformative discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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