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TSEN15 Knockout Cell Lines

Gene: TSEN15

Official Full Name: tRNA splicing endonuclease subunit 15provided by HGNC

Gene Summary: This gene encodes a subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from tRNA precursors. Alternative splicing results in multiple transcript variants. There is a pseudogene of this gene on chromosome 17. [provided by RefSeq, Jul 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30514 TSEN15 Knockout cell line (HeLa) Human TSEN15 1:3~1:6 Negative Online Inquiry
KO30515 TSEN15 Knockout cell line (HCT 116) Human TSEN15 1:2~1:4 Negative Online Inquiry
KO30516 TSEN15 Knockout cell line (HEK293) Human TSEN15 1:3~1:6 Negative Online Inquiry
KO30517 TSEN15 Knockout cell line (A549) Human TSEN15 1:3~1:4 Negative Online Inquiry

Background

TSEN15 Gene Knockout Cell Lines represent a cutting-edge biological tool designed for the investigation of gene function and protein interactions relevant to cellular processes. These knockout cell lines are engineered to have a specific gene—TSEN15—deactivated, allowing researchers to study the downstream effects of this gene’s loss on cellular homeostasis, signaling pathways, and metabolic activities. The precise mechanism of action relies on established gene editing technologies, such as CRISPR/Cas9, which introduce targeted mutations to disable the TSEN15 gene, providing a robust platform for both in vitro and in vivo studies.

The scientific importance of TSEN15 Gene Knockout Cell Lines cannot be overstated, as they play a critical role in elucidating the pathophysiological mechanisms associated with TSEN dysfunction, which has implications in neurodegenerative diseases and cellular stress responses. These cell lines facilitate high-throughput screening, enabling researchers to evaluate pharmacological agents, investigate gene compensation mechanisms, and comprehensively assess gene-environment interactions.

Unique selling points of TSEN15 Gene Knockout Cell Lines include their validated knockout efficiency and reproducibility, which surpass many alternative models that may not effectively mimic the knockout context. By utilizing these cell lines, researchers can save significant time and resources in their experimental setups, ensuring less variability and more reliable data.

In a landscape where precision is paramount, TSEN15 Gene Knockout Cell Lines provide unparalleled insights for experimental assays, making them invaluable for researchers aiming to explore therapeutic targets. Our company boasts a wealth of expertise in developing high-quality biological research tools and is committed to supporting the scientific community with innovative solutions that advance molecular biology and genetics research.

Please note that all services are for research use only. Not intended for any clinical use.

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