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TSC22D1 Knockout Cell Lines

Gene: TSC22D1

Official Full Name: TSC22 domain family member 1provided by HGNC

Gene Summary: This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33779 TSC22D1 Knockout cell line (HeLa) Human TSC22D1 1:3~1:6 Negative Online Inquiry
KO33780 TSC22D1 Knockout cell line (HCT 116) Human TSC22D1 1:2~1:4 Negative Online Inquiry
KO33781 TSC22D1 Knockout cell line (HEK293) Human TSC22D1 1:3~1:6 Negative Online Inquiry
KO33782 TSC22D1 Knockout cell line (A549) Human TSC22D1 1:3~1:4 Negative Online Inquiry

Background

TSC22D1 Gene Knockout Cell Lines are specialized cell lines in which the TSC22 domain family member 1 (TSC22D1) gene has been knocked out, leading to the disruption of its normal function. TSC22D1 is implicated in various biological processes, including cell proliferation, apoptosis, and inflammatory responses, making these cell lines critical tools for studying its role in disease mechanisms, particularly in cancer and immune disorders.

The knockout of TSC22D1 results in a loss of its regulatory functions, enabling researchers to examine the impact on pathways that regulate stress responses, cellular differentiation, and immune system activities. By observing the resultant phenotypic changes in these cell lines, scientists can elucidate the molecular mechanisms underlying the actions of TSC22D1, facilitating drug discovery and therapeutic development efforts targeting related pathways.

In a clinical research setting, TSC22D1 Gene Knockout Cell Lines are invaluable for elucidating the gene's association with various pathologies, particularly those involving aberrant cell growth and immune dysregulation. Their application extends to pharmacological studies, where they provide a platform to test the efficacy of novel therapies aimed at cancers that exhibit altered TSC22D1 expression.

What sets our TSC22D1 Gene Knockout Cell Lines apart from competitor offerings are the rigorous validation processes they undergo, ensuring high specificity and reproducibility in experimental results. Additionally, our cell lines are derived from well-characterized backgrounds, simplifying the integration into existing research workflows.

For researchers and clinicians aiming to gain deeper insights into the TSC22D1 gene's role and its related pathways, these knockout cell lines are a critical resource. They are designed not only to advance your research initiatives but also to enhance the potential for real-world clinical applications.

As an established leader in providing high-quality biological products, our company is committed to supporting scientific inquiry and innovation, ensuring that our products meet the highest standards of reliability and performance for researchers across various fields.

Please note that all services are for research use only. Not intended for any clinical use.

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