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TRMT13 Knockout Cell Lines

Gene: TRMT13

Official Full Name: tRNA methyltransferase 13 homologprovided by HGNC

Gene Summary: Predicted to enable tRNA methyltransferase activity. Predicted to be involved in tRNA methylation. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21710 TRMT13 Knockout cell line (HeLa) Human TRMT13 1:3~1:6 Negative Online Inquiry
KO21711 TRMT13 Knockout cell line (HCT 116) Human TRMT13 1:2~1:4 Negative Online Inquiry
KO21712 TRMT13 Knockout cell line (HEK293) Human TRMT13 1:3~1:6 Negative Online Inquiry
KO21713 TRMT13 Knockout cell line (A549) Human TRMT13 1:3~1:4 Negative Online Inquiry

Background

TRMT13 Gene Knockout Cell Lines represent a pivotal advancement in molecular biology research, specifically designed to investigate the functional roles of the TRMT13 gene. These cell lines have been engineered through precise CRISPR-Cas9 technology to create a complete knockout of the TRMT13 gene, allowing for the study of its contributions to cellular processes such as RNA methylation and gene expression regulation.

The primary mechanism of action hinges on disrupting the normal function of the TRMT13 gene, which encodes a tRNA methyltransferase involved in post-transcriptional modifications. By silencing this gene, researchers can observe its effects on cellular biology, enabling the exploration of metabolic pathways and translational control mechanisms that influence cellular growth, differentiation, and stress responses.

The scientific importance of TRMT13 Gene Knockout Cell Lines extends to both fundamental and applied research contexts. In basic research, these lines facilitate the elucidation of RNA modification pathways, while in clinical settings, they offer insights into potential therapeutic targets for diseases linked to mitochondrial dysfunction or abnormalities in RNA metabolism. This duality enhances the applicability of findings derived from experiments performed using these cell lines.

What sets TRMT13 Gene Knockout Cell Lines apart from traditional knockout models is their high specificity, efficiency, and reliability, coupled with stringent quality control during production. While alternative models may carry background genetic variations impacting experimental outcomes, these cell lines provide a consistent genetic background, ensuring reproducibility in research findings.

Researchers and clinicians should be aware of the significant value TRMT13 Gene Knockout Cell Lines bring to their work, including increased resolution of results, accelerated discovery timelines, and enhanced understanding of gene function in both normal and pathological contexts. Our company specializes in the development of innovative genetic tools backed by robust scientific expertise and commitment to quality, ensuring that every product we offer empowers advancement in biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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